We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time. Find out more Skip to Main Content

Best of 2016

Below is a roundup of the most popular research from the ESHRE journals. We have curated a collection of articles that have been read the most and received a large amount of media and online attention.

Most popular articles from 2016

Human Reproduction

Assisted reproductive technology in Europe, 2011: results generated from European registers by ESHRE
The European IVF-Monitoring Consortium (EIM) for the European Society of Human Reproduction and Embryology (ESHRE), M.S. Kupka T. D'Hooghe, A.P. Ferraretti, et al.

Revised guidelines for good practice in IVF laboratories (2015)
The ESHRE Guideline Group on Good Practice in IVF Labs, Maria José De los Santos, Susanna Apter, et al.

ESHRE Guideline: management of women with premature ovarian insufficiency
The ESHRE Guideline Group on POI, L. Webber, M. Davies, R. Anderson, et al.

The end of donor anonymity: how genetic testing is likely to drive anonymous gamete donation out of business
Joyce C. Harper, Debbie Kennett, and Dan Reisel

Conventional ovarian stimulation and single embryo transfer for IVF/ICSI. How many oocytes do we need to maximize cumulative live birth rates after utilization of all fresh and frozen embryos?
Panagiotis Drakopoulos, Christophe Blockeel, Dominic Stoop, Michel Camus, et al.

Autologous cell therapy with CD133+ bone marrow-derived stem cells for refractory Asherman's syndrome and endometrial atrophy: a pilot cohort study
Xavier Santamaria, Sergio Cabanillas, Irene Cervelló, et al.

Consistent and reproducible outcomes of blastocyst biopsy and aneuploidy screening across different biopsy practitioners: a multicentre study involving 2586 embryo biopsies
Antonio Capalbo, Filippo Maria Ubaldi, Danilo Cimadomo, et al.

The Thessaloniki ESHRE/ESGE consensus on diagnosis of female genital anomalies
Grigoris F. Grimbizis, Attilio Di Spiezio Sardo, Sotirios H. Saravelos, et al.

Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes
Trapphoff, M. Heiligentag, D. Dankert, et al.

Assisted reproductive technology use and outcomes among women with a history of cancer
Barbara Luke, Morton B. Brown, Stacey A. Missmer, et al.

Human Reproduction Update

The effects of chemical and physical factors on mammalian embryo culture and their importance for the practice of assisted human reproduction
Petra L. Wale and David K. Gardner

Surrogacy: outcomes for surrogate mothers, children and the resulting families—a systematic review
Viveca Söderström-Anttila, Ulla-Britt Wennerholm, Anne Loft, et al.

Endometrial stem/progenitor cells: the first 10 years
Caroline E. Gargett, Kjiana E. Schwab, and James A. Deane

Gamete activation: basic knowledge and clinical applications
Elisabetta Tosti and Yves Ménézo

Genome engineering through CRISPR/Cas9 technology in the human germline and pluripotent stem cells
R. Vassena, B. Heindryckx. R. Peco, et al.

A systematic review on endometriosis during pregnancy: diagnosis, misdiagnosis, complications and outcomes
Umberto Leone Roberti Maggiore, Simone Ferrero, Giorgia Mangili, et al.

Extracellular vesicles: roles in gamete maturation, fertilization and embryo implantation
Ronit Machtinger, Louise C. Laurent, and Andrea A. Baccarelli

Oocyte cryopreservation: where are we now?
Catrin E. Argyle, Joyce C. Harper, and Melanie C. Davies

Metformin and lifestyle modification in polycystic ovary syndrome: systematic review and meta-analysis
Negar Naderpoor, Soulmaz Shorakae, Barbora de Courten, et al.

The ICSI procedure from past to future: a systematic review of the more controversial aspects
Negar Naderpoor, Soulmaz Shorakaem Barbora de Courten, et al.

Molecular Human Reproduction

Bioinformatics approaches to single-cell analysis in developmental biology
Dicle Yalcin, Zeynep M. Hakguder, and Hasan H. Out

The importance of neuronal growth factors in the ovary
S. Streiter, B. Fisch, B. Sabbah, A. Ao, and R. Abir

Does mouse embryo primordial germ cell activation start before implantation as suggested by single-cell transcriptomics dynamics?
Daniela Gerovska and Marcos J. Araúzo-Bravo

Whole exome sequencing in recurrent early pregnancy loss
Ying Qiao, Jiadi Wen, and Flamingo Tang

Granulosa cell and oocyte mitochondrial abnormalities in a mouse model of fragile X primary ovarian insufficiency
Carola Conca Dioguardi, Bahar Uslu, Monique Haynes, et al.

Ultrastructure of human oocytes after in vitro maturation
Giovanni Coticchio, Mariabeatrice Dal Canto, Rubens Fadini, et al.

Establishment of a confluent monolayer model with human primary trophoblast cells: novel insights into placental glucose transport
Xiao Huang, Michael Lüthi, Edgar C. Ontsouka, et al.

What we can learn from single-cell analysis in development
Michele Boiani and Jose B. Cibelli

Oxidative stress damage-associated molecular signaling pathways differentiate spontaneous preterm birth and preterm premature rupture of the membranes
Eryn H. Dutta, Faranak Behnia, Istvan Boldogh, et al.

Heat Shock Protein member A2 forms a stable complex with angiotensin converting enzyme and protein disulfide isomerase A6 in human spermatozoa
Elizabeth G. Bromfield, Eileen A. McLaughlin, Robert John Aitken, and Brett Nixon

Top Altmetric articles

Semen quality of young adult ICSI offspring: the first results
F. Belva, M. Bonduelle, and M. Roelants

Expression of Syncytin 1 (HERV-W), in the preimplantation human blastocyst, embryonic stem cells and trophoblast cells derived in vitro
Bikem Soygur and Harry Moore

Corticosteroid therapy in assisted reproduction – immune suppression is a faulty premise
Sarah A. Robertson, Min Jin, Danqing Yu, et al.

Anti-Müllerian hormone serum concentrations of women with germline BRCA1 or BRCA2 mutations
Kelly-Anne Phillips, Ian M. Collins, Roger L. Milne, et al.

Seminal plasma transforming growth factor-β, activin A and follistatin fluctuate within men over time
David J. Sharkey, Kelton P. Tremellen, Nancy E. Briggs, et al.

Population variation in age-related decline in male salivary testosterone
Peter T. Ellison, Richard G. Bribiescas, Gillian R. Bentley, et al.

Prevalence of infertility and help seeking among 15 000 women and men
J. Datta, M.J. Palmer, C. Tanton, et al.

Is underage abortion associated with adverse outcomes in early adulthood? A longitudinal birth cohort study up to 25 years of age
Suvi Leppälahti, Oskari Heikinheimo, Ilkka Kalliala, Päivi Santalahti, and Mika Gissler

ESHRE in the news

Influence of embryo culture medium (G5 and HTF) on pregnancy and perinatal outcome after IVF: a multicenter RCT
Sander H.M. Kleijkers, Eleni Mantikou, Els Slappendel, et al.

Editorial: Peanut Butter
J.L.H. (Hans) Evers

Time to take human embryo culture seriously
Arne Sunde, Daniel Brison, John Dumoulin

Non-growing follicle density is increased following adriamycin, bleomycin, vinblastine and dacarbazine (ABVD) chemotherapy in the adult human ovary
M. McLaughlin, T.W. Kelsey, W.H.B. Wallace, R.A. Anderson, and E.E. Telfer

International Committee for Monitoring Assisted Reproductive Technologies world report: Assisted Reproductive Technology 2008, 2009 and 2010
S. Dyer, G.M. Chambers, J. de Mouzon, et al.

Santa Claus in the fertility clinic
J.L.H. (Hans) Evers

Parental contributions to early embryo development: influences of urinary phthalate and phthalate alternatives among couples undergoing IVF treatment
Haotian Wu, Lisa Ashcraft, Brian W. Whitcomb, et al.

Disparities between online assisted reproduction patient education for same-sex and heterosexual couples
Helen Jin and Shoumita Dasgupta


We are delighted to announce launch of Human Reproduction Open (HROpen), the new, official open access journal from the European Society of Human Reproduction and Embryology (ESHRE). HROpen seeks to improve the understanding of reproductive medicine, and improve the quality of clinical care by making scientific research freely accessible to those providing or seeking treatment. HROpen is now accepting submissions of studies addressing clinical, biological, environmental, ethical, and social aspects of reproductive medicine in its wider sense – beyond infertility and assisted reproduction.

Submit your papers to HROpen now
This Feature Is Available To Subscribers Only

Sign In or Create an Account

This PDF is available to Subscribers Only

View Article Abstract & Purchase Options

For full access to this pdf, sign in to an existing account, or purchase an annual subscription.

Subscribe Now