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Figure 2. The rates of antipsychotic monotherapy and complete antipsychotic monotherapy in the clozapine-available institution (CAI) group and the clozapine-unavailable institution (CUI) group when patients who were prescribed clozapine were excluded. (A) The rate of antipsychotic monotherapy in the CAI group

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The rates of antipsychotic monotherapy and complete antipsychotic monothera...

Published: 28 March 2025

Figure 1. The rates of antipsychotic monotherapy and complete antipsychotic monotherapy between the clozapine-available institution (CAI) group and the clozapine-unavailable institution (CUI) group. (A) The rate of antipsychotic monotherapy in the CAI group was significantly higher than that in the CUI group.

Journal Article

Associations between clozapine availability, the diagnosis of treatment-resistant schizophrenia subgroups, antipsychotic monotherapy, and concomitant psychotropics among patients with schizophrenia: a real-world nationwide study

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Shinichiro Ochi and others

International Journal of Neuropsychopharmacology, Volume 28, Issue 4, April 2025, pyaf011, https://doi.org/10.1093/ijnp/pyaf011

Published: 28 March 2025

Supplementary data

Image

The rates of antipsychotic monotherapy and complete antipsychotic monothera...

Published: 28 March 2025

Figure 3. The rates of antipsychotic monotherapy and complete antipsychotic monotherapy between the clozapine-available institution (CAI) group and the clozapine-unavailable institution (CUI) group, regardless of whether treatment-resistant schizophrenia subgroups were described. (A) The rate of antipsychotic

Journal Article

ACCEPTED MANUSCRIPT

Neuropathic Pain impairs Sleep Architecture, NREM sleep and Reticular Thalamic Neuronal activity

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Martha López-Canul and others

International Journal of Neuropsychopharmacology, pyaf017, https://doi.org/10.1093/ijnp/pyaf017

Published: 23 March 2025

Journal Article

Examination of the relationship between D-amino acid profiles and cognitive function in individuals with mild cognitive impairment: a machine learning approach

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Sou Sugiki and others

International Journal of Neuropsychopharmacology, Volume 28, Issue 4, April 2025, pyaf016, https://doi.org/10.1093/ijnp/pyaf016

Published: 15 March 2025

Supplementary data

Image

Clinical trial flow. *In the comparison of the correlation between venous p...

in Examination of the relationship between D-amino acid profiles and cognitive function in individuals with mild cognitive impairment: a machine learning approach

Published: 15 March 2025

Figure 1. Clinical trial flow. *In the comparison of the correlation between venous plasma and fingertip whole blood for D-Pro (%) or D-Ala (%), outliers are defined as those with standardized residuals exceeding 2.0.

Image

(A) Correlation comparison of amino acid concentrations in venous and finge...

in Examination of the relationship between D-amino acid profiles and cognitive function in individuals with mild cognitive impairment: a machine learning approach

Published: 15 March 2025

Figure 2. (A) Correlation comparison of amino acid concentrations in venous and fingertip blood. Red dots indicate data points with outliers. (B) Correlation comparison of amino acid concentrations and D-amino acid (%) in venous and fingertip blood, excluding outliers.

Image

Scatterplots showing group differences in the concentration of D-Pro (%) an...

in Examination of the relationship between D-amino acid profiles and cognitive function in individuals with mild cognitive impairment: a machine learning approach

Published: 15 March 2025

Figure 3. Scatterplots showing group differences in the concentration of D-Pro (%) and D-Ala (%) in whole fingertip blood. Black horizontal lines denote the median value. Differences in each concentration between the cognitively normal (CN) group and the suspected MCI group (MCI) by sex were explored using th

Image

(A) The ROC curve when a kernel SVM model was constructed using relatively ...

in Examination of the relationship between D-amino acid profiles and cognitive function in individuals with mild cognitive impairment: a machine learning approach

Published: 15 March 2025

Figure 4. (A) The ROC curve when a kernel SVM model was constructed using relatively easily obtainable participant background information (sex, age, BMI, education years, number of people living together, and family composition), and LOOCV was performed. (B) The ROC curve when a kernel SVM model was construct

Image

(A) The ROC curve (kernel SVM, LOOCV) when the criterion for sus-MCI was se...

in Examination of the relationship between D-amino acid profiles and cognitive function in individuals with mild cognitive impairment: a machine learning approach

Published: 15 March 2025

Figure 5. (A) The ROC curve (kernel SVM, LOOCV) when the criterion for sus-MCI was set to MMSE ≤ 26. (B) The ROC curve (kernel SVM, LOOCV) when the criterion for sus-MCI was set to MMSE ≤ 27. (C) The ROC curve (kernel SVM, LOOCV) when the borderline MMSE scores of 26 and 27 were excluded. LOOCV, leave-one-out

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The rates of antipsychotic monotherapy and complete antipsychotic monothera...

The rates of antipsychotic monotherapy and complete antipsychotic monothera...

Associations between clozapine availability, the diagnosis of treatment-resistant schizophrenia subgroups, antipsychotic monotherapy, and concomitant psychotropics among patients with schizophrenia: a real-world nationwide study

The rates of antipsychotic monotherapy and complete antipsychotic monothera...

Neuropathic Pain impairs Sleep Architecture, NREM sleep and Reticular Thalamic Neuronal activity

Examination of the relationship between D-amino acid profiles and cognitive function in individuals with mild cognitive impairment: a machine learning approach

Clinical trial flow. *In the comparison of the correlation between venous p...

(A) Correlation comparison of amino acid concentrations in venous and finge...

Scatterplots showing group differences in the concentration of D-Pro (%) an...

(A) The ROC curve when a kernel SVM model was constructed using relatively ...

(A) The ROC curve (kernel SVM, LOOCV) when the criterion for sus-MCI was se...

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