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Figure 1. Schematic diagram representing study workflow. CTRL, control; F1, fraction 1; F2, fraction 2; MDD, major depressive disorder. Figure was created using BioRender.

Image

Quality assessment of EV isolation. (A) Left: Representative stain-free ima...

in International Journal of Neuropsychopharmacology > Profiling Small RNA From Brain Extracellular Vesicles in Individuals With Depression

Published: 08 March 2024

Figure 2. Quality assessment of EV isolation. (A) Left: Representative stain-free image showing total protein loading for western blot. Right: Representative western blot for Calnexin, BiP, VDAC, CD9, and TSG101 in F1, F2, WB, and PC. (B) Average distribution of particle size from 20 subjects (5 M-CTRL, 5 M-M

Image

Comparative analysis of EV miRNAs in males and females. (A) Volcano plots s...

in International Journal of Neuropsychopharmacology > Profiling Small RNA From Brain Extracellular Vesicles in Individuals With Depression

Published: 08 March 2024

Figure 3. Comparative analysis of EV miRNAs in males and females. (A) Volcano plots showing altered miRNA expression for males (blue) and females (orange) at a cut-off of P value ≤ .05. (B) Correlation plots between normalized sequencing counts and qPCR expression of the 3 top miRNAs for males (blue) and fe

Journal Article

Blunted Cortisol Response to Acute Psychosocial Stress in Women With Premenstrual Dysphoric Disorder

PDF

Ajna Hamidovic and others

International Journal of Neuropsychopharmacology, Volume 27, Issue 3, March 2024, pyae015, https://doi.org/10.1093/ijnp/pyae015

Published: 07 March 2024

Image

The effect of time and diagnosis on serum cortisol. Considering the baselin...

in International Journal of Neuropsychopharmacology > Blunted Cortisol Response to Acute Psychosocial Stress in Women With Premenstrual Dysphoric Disorder

Published: 07 March 2024

Figure 1. The effect of time and diagnosis on serum cortisol. Considering the baseline, PMDD participants had lower cortisol levels at +40 ( P ≤ .01), +50 ( P ≤ .01), +65 ( P ≤ .01), and +90 ( P ≤ .01) minutes from the start of TSST relative to the healthy controls. The intervals represent confidence inte

Image

Change over time in Oxford Depression Questionnaire (ODQ) score and subscal...

in International Journal of Neuropsychopharmacology > Emotional Blunting in Depression in the PREDDICT Clinical Trial: Inflammation-Stratified Augmentation of Vortioxetine With Celecoxib

Published: 05 March 2024

Figure 2. Change over time in Oxford Depression Questionnaire (ODQ) score and subscales over time by treatment group. Plots of the mean of vortioxetine + placebo and vortioxetine + celecoxib scores at baseline, week 8, 3-month follow-up, and 6-month follow-up time points for a ODQ total score, b ODQ gener

Image

Change over time in Oxford Depression Questionnaire (ODQ) score and subscal...

in International Journal of Neuropsychopharmacology > Emotional Blunting in Depression in the PREDDICT Clinical Trial: Inflammation-Stratified Augmentation of Vortioxetine With Celecoxib

Published: 05 March 2024

Figure 3. Change over time in Oxford Depression Questionnaire (ODQ) score and subscales over time by treatment group and high sensitivity C-reactive protein (hsCRP) strata. Plots of the mean respective scores at baseline, week 8, 3-month follow-up, and 6-month follow-up time points of participants treated wit

Journal Article

Emotional Blunting in Depression in the PREDDICT Clinical Trial: Inflammation-Stratified Augmentation of Vortioxetine With Celecoxib

PDF

Emma Sampson and others

International Journal of Neuropsychopharmacology, Volume 27, Issue 3, March 2024, pyad066, https://doi.org/10.1093/ijnp/pyad066

Published: 05 March 2024

Image

PREDDICT RCT schedule of treatments and assessments^a. ...

in International Journal of Neuropsychopharmacology > Emotional Blunting in Depression in the PREDDICT Clinical Trial: Inflammation-Stratified Augmentation of Vortioxetine With Celecoxib

Published: 05 March 2024

Figure 1. PREDDICT RCT schedule of treatments and assessments a . a Adapted from Kavakbasi et al. , 2023 . A, administration of the Oxford Depression Questionnaire (ODQ) assessment; B, collection of peripheral venous blood; R, randomization. Participation in the trial and continued treatment with vo

Image

Forest plot of comparison in the risk ratio of conversion to psychosis in t...

in International Journal of Neuropsychopharmacology > Network Meta-Analysis Indicates Superior Effects of Omega-3 Polyunsaturated Fatty Acids in Preventing the Transition to Psychosis in Individuals at Clinical High-Risk

Published: 26 February 2024

Figure 3. Forest plot of comparison in the risk ratio of conversion to psychosis in the network meta-analysis for transition outcome at 6, 12, and ≥24 months in 2 levels: pharmacological/nutritional interventions group (on the left) and pharmacological/nutritional interventions plus psychotherapy group (on th

Image

Network plots of direct comparisons in the network meta-analysis for transi...

Published: 26 February 2024

Figure 2. Network plots of direct comparisons in the network meta-analysis for transition outcome at 6, 12, and ≥24 months in 2 levels: pharmacological/nutritional interventions group (on the left) and pharmacological/nutritional interventions plus psychotherapy group (on the right). The width of the lines is

Journal Article

Network Meta-Analysis Indicates Superior Effects of Omega-3 Polyunsaturated Fatty Acids in Preventing the Transition to Psychosis in Individuals at Clinical High-Risk

PDF

Chengfeng Chen and others

International Journal of Neuropsychopharmacology, Volume 27, Issue 3, March 2024, pyae014, https://doi.org/10.1093/ijnp/pyae014

Published: 26 February 2024

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Corrigendum to: Anhedonia, Apathy, Pleasure, and Effort-Based Decision-Making in Adult and Adolescent Cannabis Users and Controls

Profiling Small RNA From Brain Extracellular Vesicles in Individuals With Depression

Schematic diagram representing study workflow. CTRL, control; F1, fraction...

Quality assessment of EV isolation. (A) Left: Representative stain-free ima...

Comparative analysis of EV miRNAs in males and females. (A) Volcano plots s...

Blunted Cortisol Response to Acute Psychosocial Stress in Women With Premenstrual Dysphoric Disorder

The effect of time and diagnosis on serum cortisol. Considering the baselin...

Change over time in Oxford Depression Questionnaire (ODQ) score and subscal...

Change over time in Oxford Depression Questionnaire (ODQ) score and subscal...

Emotional Blunting in Depression in the PREDDICT Clinical Trial: Inflammation-Stratified Augmentation of Vortioxetine With Celecoxib

PREDDICT RCT schedule of treatments and assessments^a. ...

Forest plot of comparison in the risk ratio of conversion to psychosis in t...

Network plots of direct comparisons in the network meta-analysis for transi...

Network Meta-Analysis Indicates Superior Effects of Omega-3 Polyunsaturated Fatty Acids in Preventing the Transition to Psychosis in Individuals at Clinical High-Risk

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