INTERVENTION FIDELITY IN THE FAMILY-CENTERED FUNCTION-FOCUSED CARE INTERVENTION

Abstract This session will provide a description of the treatment fidelity (TF) plan from the Family-centered Function-focused Care (Fam-FFC) trial. Components of the TF plan, measures, procedures for implementation, and findings will be presented, and discussed within the context of the COVID-19 pandemic. The components of the Fam-FFC TF plan and results include: 1) Delivery based on completion of the steps in Fam-FFC ; 2) Receipt based on evidence of Staff knowledge of Fam-FFC (percentage of nursing staff that demonstrated test scores above 80%); 3) Enactment based on achievement of goals using the Goal Attainment Scale ; completion of the Fam-Path Audit of bedside goals and treatment plans, post-acute follow-up and plan update ; and evidence of Fam-FFC based on the Fam-FFC Behavior Checklist (80% staff performance of Fam-FFC). The TF plan demonstrated evidence of delivery, receipt and enactment of study activities. Findings will be used to develop an implementation trial.


GENDER DIFFERENCES IN INTERACTIONS AND WELL-BEING AMONG HOSPITALIZED PATIENTS LIVING WITH DEMENTIA
Anju Paudel 1 , Marie Boltz 2 , and Barbara Resnick 3 , 1. Penn State Ross and Carol Nese College of Nursing,State College,Pennsylvania,United States,2. Penn State,Pennsylvania State University,Pennsylvania,United States,3. University of Maryland,Baltimore,Maryland,United States While the incidence of dementia is generally higher in women compared to men, gender differences in interactions and well-being in dementia is still unclear. This study examined gender differences in interactions and well-being among hospitalized patients living with dementia. A total of 140 hospitalized patients (53% female and 47% male) were included in the analysis. On average, the participants were 81.43 years old (SD= 8.29), had positive interactions with staff based on higher scores on Quality of Interaction Schedule, QUIS (5.81, SD= 1.36), and fair emotional well-being based on lower scores on Cornell Scale for Depression in Dementia, CSDD (7.79, SD= 5.59). Although men seemed to have more positive interactions (male=6.07, SD=1.13; female=5.59, SD=1.51) and greater wellbeing (male=7.52, SD=4.77; female=8.03, SD=6.25) than women, there were no statistically significant gender differences observed in linear models with appropriate covariates. Future work should continue to explore gender differences in interactions and well-being.

PREDICTORS OF THE DESIRE TO INSTITUTIONALIZE IN CARE PARTNERS OF HOSPITALIZED PERSONS WITH DEMENTIA AT DISCHARGE Ashley Kuzmik, Penn State University, University Park, Pennsylvania, United States
Hospitalized persons with dementia are more likely to be discharged to long-term nursing home care as compared to persons without dementia. The desire to seek this care is due in large part to the inability of family care partners to continue to provide care at home. This study aimed to identify predictors of desire to institutionalize (DTI) in care partners of persons with dementia at hospital discharge. A stepwise multiple linear regression was done to examine the dyad factors among 434 patient and care partners associated with DTI . Lower preparedness for caregiving (p < .001), higher caregiver strain (p = .039), cohabitation (p < .001) and care partner race (White; p = .016) were associated with DTI. Findings underscore the need to assess family preparedness for caregiving, strain, and living situation upon admission, and suggest the need to examine racial differences in the desire to seek nursing home care.

INTERVENTION FIDELITY IN THE FAMILY-CENTERED FUNCTION-FOCUSED CARE INTERVENTION Barbara Resnick, University of Maryland, Baltimore, Maryland, United States
This session will provide a description of the treatment fidelity (TF) plan from the Family-centered Function-focused Care (Fam-FFC) trial. Components of the TF plan, measures, procedures for implementation, and findings will be presented, and discussed within the context of the COVID-19 pandemic. The components of the Fam-FFC TF plan and results include: 1) Delivery based on completion of the steps in Fam-FFC ; 2) Receipt based on evidence of Staff knowledge of Fam-FFC (percentage of nursing staff that demonstrated test scores above 80%); 3) Enactment based on achievement of goals using the Goal Attainment Scale ; completion of the Fam-Path Audit of bedside goals and treatment plans, post-acute follow-up and plan update ; and evidence of Fam-FFC based on the Fam-FFC Behavior Checklist (80% staff performance of Fam-FFC). The TF plan demonstrated evidence of delivery, receipt and enactment of study activities. Findings will be used to develop an implementation trial.

MAXWELL A. POLLACK AWARD FOR CONTRIBUTIONS TO HEALTH AGING PRESENTATION AND LECTURE Chair: Philip Rozario
The Maxwell A. Pollack Award for Contributions to Health Aging Lecture will feature an address by the 2021 Pollack Award recipient Namkee G. Choi, PhD, FGSA, of the University of Texas at Austin. This session will also include the presentation of the 2022 Maxwell A. Pollack Award to recipient Nancy Morrow-Howell, MSW, PhD, FGSA, of Washington University in St. Louis. The Maxwell A. Pollack Award for Contributions to Healthy Aging Award recognizes instances of practice informed by research and analysis, research that has directly improved policy or practice, and distinction in bridging the worlds of research and practice.

ADDRESSING THE MENTAL HEALTH NEEDS OF HOMEBOUND OLDER ADULTS IN AGING SERVICE SETTINGS Namkee Choi, University of Texas at Austin, Austin, Texas, United States
Despite significant and urgent mental health needs among low-income homebound older adults, the existing mental health service systems' reach for these older adults is almost nonexistent. Given the current and projected geriatric mental health workforce shortages, innovative approaches are needed to better serve these underserved older adults. This presentation will focus on a series of randomized clinical trials that tested acceptable and feasible mental health service delivery models for homebound older adults who are served by aging service network agencies that provide hot meals and case management. Findings from the real-world effectiveness trials of tele-delivered behavioral activation treatment for depression and loneliness by bachelor's-level lay counselors who are embedded in aging service agencies will be shared. Ways to promote a wider adoption of scalable and sustainable mental health service delivery models for homebound older adults will be discussed.

HUMAN AGING INTERVENTIONS Chair: Daniel Parker
Biological aging is the greatest risk factor for multiple non-communicable diseases affecting multiple organ systems. Evidence from animal studies suggest that the rate of biological aging is modifiable and that slowing the rate of biological aging may decrease the incidence of age-related morbidity and mortality. Based on these findings, several approaches are currently being studied to slow the rate of biological aging in humans. This symposium features internationally renowned aging research scientists whose work focuses on clinical interventions to modify biological aging in humans. We will hear from Rajagopal Sekhar from the Baylor College of Medicine who will present his research on "Improving oxidative stress, mitochondrial dysfunction, inflammaging, aging hallmarks and muscle strength in older adults: the novel role of GlyNAC and the 'Power of 3'"; Jamie Justice from the Wake Forest School of Medicine will present her work on "Response to dietary restriction interventions in older adults: biomarkers of cellular senescence and biological aging"; Reem Waziry from the Columbia University Mailman School of Public Health will present her work "Does Caloric Restriction Slow the Process of Biological Aging in Non-Obese Healthy Adults? Evidence from the CALERIE™ Trial"; and Daniel Parker from the Duke University School of Medicine will present his work "Does APOE genotype moderate the impact of diet modification and exercise training on age-related outcomes?". Attendees will learn about recent advances in interventions targeting human aging. Daniel Parker, P. Murali Doraiswamy, William Kraus, and Kim Huffman, Duke University School of Medicine, Durham, North Carolina, United States Midlife cardiometabolic risk factors are associated with an increased risk of Alzheimer's dementia (AD). Moderate calorie restriction (CR) in healthy, non-obese young and middle-aged adults improves cardiometabolic risk factors. Plasma concentrations of amyloid β oligomers (Aβ-42 and Aβ-40) and total tau are emerging biomarkers of AD pathology. Our objective was to determine the impact of two years of CR in healthy young and middle-aged adults on Aβ-42, Aβ-40, and total tau in the Comprehensive Assessment of Long term Effects of Reducing Intake of Energy (CALERIE) Study. Participants were randomized 2:1 to 24 months of CR (prescribed as 25% reduction in baseline calorie requirements) versus an ad libitum (AL) diet. We quantified plasma Aβ-42, Aβ-40, and total tau using the ultrasensitive single molecule array (SIMOA) technology at baseline and two years in a subset of CALERIE (N=133). We used linear regression to evaluate the impact of CR, including age, sex, and presence/absence of the APOE-ε4 risk allele as covariates. We hypothesized that there would be differential CR effects based on APOE-ε4 carrier status; to test this, we included an interaction term. As compared to AL, there was a trend towards decreased Aβ-40, controlling for age, baseline Aβ-40 concentrations, and APOE-ε4 carrier status (β=-12.59, 95% CI[-27.14, 1.96], p=0.093) with 12% (average achieved) CR. The CR*APOE-ε4 carrier status interaction term was significant at a pre-defined threshold of p<0.10 (p=0.062).