Advance articles
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Research Article 28 April 2025
Isavuconazole therapeutic drug monitoring and association with adverse events
Emily Huang and othersJournal of Antimicrobial Chemotherapy, dkaf128, https://doi.org/10.1093/jac/dkaf128 -
Research Article 24 April 2025
Antibiotic treatment of Stenotrophomonas maltophilia bacteraemia: does trimethoprim/sulfamethoxazole dose affect clinical outcomes?
Wei-Ping Chen and othersJournal of Antimicrobial Chemotherapy, dkaf131, https://doi.org/10.1093/jac/dkaf131 -
Research Article 23 April 2025
Impact of the inoculum effect on cefepime activity against AmpC-hyperproducing Enterobacter spp.: insights into resistance mechanisms
Ángel Rodríguez-Villodres and othersJournal of Antimicrobial Chemotherapy, dkaf122, https://doi.org/10.1093/jac/dkaf122 -
Research Article 22 April 2025
Effect of body mass index on the timing of therapeutic drug monitoring—guided dalbavancin dosing in patients with osteoarticular infections
Dario Cattaneo and othersJournal of Antimicrobial Chemotherapy, dkaf132, https://doi.org/10.1093/jac/dkaf132 -
Brief Report 21 April 2025
Ultrasound for long-acting injectable cabotegravir and rilpivirine in transgender individuals with implants: a new opportunity for normalization
Jesús Troya and othersJournal of Antimicrobial Chemotherapy, dkaf127, https://doi.org/10.1093/jac/dkaf127 -
Research Article 21 April 2025
Therapeutic drug monitoring in anti-tuberculosis treatment: a systematic review
Youssra Metarfi and othersJournal of Antimicrobial Chemotherapy, dkaf126, https://doi.org/10.1093/jac/dkaf126 -
Research Article 18 April 2025
Changing epidemiology of MRSA-CC398 in Spanish hospitals located in areas with different pig farming densities: a 2023 multicentre study
Allelen Campaña-Burguet and othersJournal of Antimicrobial Chemotherapy, dkaf104, https://doi.org/10.1093/jac/dkaf104 -
Research Article 17 April 2025
Interventions to improve antibiotic use among dentists: a systematic review and meta-analysis
Julieta Mendez-Romero and othersJournal of Antimicrobial Chemotherapy, dkaf118, https://doi.org/10.1093/jac/dkaf118 -
Review Article 16 April 2025
Single-cell analysis of antimicrobial compound–induced cell death of bacterial cells
Md Zahidul Islam and othersJournal of Antimicrobial Chemotherapy, dkaf116, https://doi.org/10.1093/jac/dkaf116 -
Research Article 12 April 2025
Detection of a novel SME-6 Carbapenemase in Serratia ureilytica in Germany
Kaan Kocer and othersJournal of Antimicrobial Chemotherapy, dkaf121, https://doi.org/10.1093/jac/dkaf121 -
Research Article 12 April 2025
Optimising antiretroviral therapy through a proactive treatment algorithm: a cost-effective strategy in Dutch healthcare for people with HIV
P Oosterhof and othersJournal of Antimicrobial Chemotherapy, dkaf117, https://doi.org/10.1093/jac/dkaf117 -
Research Article 11 April 2025
Ceftazidime/avibactam for the treatment of bloodstream infection due to carbapenemase-producing Enterobacterales in onco-haematologic neutropenic patients (the TARZAN study)
Enric Sastre-Escolà and othersJournal of Antimicrobial Chemotherapy, dkaf120, https://doi.org/10.1093/jac/dkaf120 -
Research Article 10 April 2025
Tetracyclines at subinhibitory concentrations are lethal for NADH peroxidase–deficient mutants of Enterococcus faecium
Valentin Wasselin and othersJournal of Antimicrobial Chemotherapy, dkaf105, https://doi.org/10.1093/jac/dkaf105 -
Research Article 10 April 2025
Clinical features and medical–surgical management overweight the inoculum effect and genotypic characteristics of MSSA in infective endocarditis
Thiziri Tala-Ighil and othersJournal of Antimicrobial Chemotherapy, dkaf115, https://doi.org/10.1093/jac/dkaf115 -
Review Article 10 April 2025
The continuing evolution of antibiotic resistance in Neisseria gonorrhoeae: past, present and future threats to effective treatment
Helen Fifer and Alan JohnsonJournal of Antimicrobial Chemotherapy, dkaf109, https://doi.org/10.1093/jac/dkaf109 -
Review Article 10 April 2025
The 2023 Garrod Lecture: Antimicrobial use and stewardship in primary care: what works, and what next?
Paul LittleJournal of Antimicrobial Chemotherapy, dkaf053, https://doi.org/10.1093/jac/dkaf053 -
Research Article 9 April 2025
Depolymerase as a potent adjunct to polymyxin for targeting KL160 pandrug-resistant Acinetobacter baumannii in a murine bacteremia model
Bai-Ling Zhang and othersJournal of Antimicrobial Chemotherapy, dkaf110, https://doi.org/10.1093/jac/dkaf110 -
Research Article 9 April 2025
Helicobacter pylori culture positivity and antimicrobial susceptibility profiles (Vancouver, Canada)
Hasan Hamze and othersJournal of Antimicrobial Chemotherapy, dkaf114, https://doi.org/10.1093/jac/dkaf114 -
Research Article 9 April 2025
Long-term durability of dolutegravir plus darunavir/cobicistat dual regimen in highly antiretroviral-experienced people with HIV (DoDaco study)
Diego Ripamonti and othersJournal of Antimicrobial Chemotherapy, dkaf119, https://doi.org/10.1093/jac/dkaf119 -
Research Article 7 April 2025
Impact of fluoroquinolone exposure on the diagnosis and prognosis of tuberculosis in immunocompromised patients: a propensity-score-matched, competing risk analysis
Sung-Woon Kang and othersJournal of Antimicrobial Chemotherapy, dkaf111, https://doi.org/10.1093/jac/dkaf111 -
Research Article 4 April 2025
Evaluation of an optimized intermittent vancomycin dosing regimen in infants
Amanda L Wilkins and othersJournal of Antimicrobial Chemotherapy, dkaf112, https://doi.org/10.1093/jac/dkaf112 -
Research Article 3 April 2025
Unravelling the genetic contributors to linezolid resistance in Mycobacterium smegmatis: insights from a transposon library
Dachuan Lin and othersJournal of Antimicrobial Chemotherapy, dkaf106, https://doi.org/10.1093/jac/dkaf106 -
Research Article 3 April 2025
Population pharmacokinetics and optimized prophylaxis dosing of cefazolin during transcatheter aortic valve implantation
C Robson and othersJournal of Antimicrobial Chemotherapy, dkaf108, https://doi.org/10.1093/jac/dkaf108 -
Research Article 3 April 2025
Holistic analysis of the determinants of antibiotic prescription in primary care in France: a cross-sectional study with nationwide panel data
Emmanuel Piednoir and othersJournal of Antimicrobial Chemotherapy, dkaf102, https://doi.org/10.1093/jac/dkaf102 -
Research Article 3 April 2025
In vitro, intracellular and in vivo synergy between amoxicillin, imipenem and relebactam against Mycobacterium abscessus
Maria Bitar and othersJournal of Antimicrobial Chemotherapy, dkaf101, https://doi.org/10.1093/jac/dkaf101 -
Brief Report 1 April 2025
Dual versus sequenial therapy using rifaximin and MTZ in a patient with intestinal methanogen overgrowth—a case report
Gernot KriegshäuserJournal of Antimicrobial Chemotherapy, dkaf107, https://doi.org/10.1093/jac/dkaf107 -
Research Article 1 April 2025
Pandemic human-associated extended-spectrum β-lactamase-producing Escherichia coli lineages of ST38, ST131 and ST141 identified in Viennese dogs
Pia Saria and othersJournal of Antimicrobial Chemotherapy, dkaf103, https://doi.org/10.1093/jac/dkaf103 -
Research Article 1 April 2025
Cross-resistance to 14-, 15- and 16-membered ring macrolides in Salmonella and Campylobacter
Ruby Singh and othersJournal of Antimicrobial Chemotherapy, dkaf094, https://doi.org/10.1093/jac/dkaf094 -
Research Article 28 March 2025
Appropriateness of loading dose and TDM in patients treated with teicoplanin: a single-centre observational retrospective cohort study comparing single-daily and thrice-weekly regimens
Alessandra Helen Behring and othersJournal of Antimicrobial Chemotherapy, dkaf097, https://doi.org/10.1093/jac/dkaf097 -
Research Article 28 March 2025
Impact of obesity on clinical outcomes in patients treated with ceftobiprole: results from Phase 3 clinical trials
Thomas L Holland and othersJournal of Antimicrobial Chemotherapy, dkaf096, https://doi.org/10.1093/jac/dkaf096 -
Research Article 28 March 2025
Adequate posology of antimicrobial therapy in the septic critically ill in continuous veno-venous hemofiltration: a single centre prospective observational study
Alberto Corona and othersJournal of Antimicrobial Chemotherapy, dkaf089, https://doi.org/10.1093/jac/dkaf089 -
Research Article 28 March 2025
Population pharmacokinetics and exposure–response relationship of the antituberculosis drug BTZ-043
Simon E Koele and othersJournal of Antimicrobial Chemotherapy, dkaf076, https://doi.org/10.1093/jac/dkaf076 -
Research Article 28 March 2025
Population pharmacokinetics of aciclovir and its major metabolite 9-carboxymethoxymethylguanine and safety profile of valaciclovir in early liver transplant recipients
Benjamin Kably and othersJournal of Antimicrobial Chemotherapy, dkaf070, https://doi.org/10.1093/jac/dkaf070 -
Research Article 27 March 2025
Quantitative performance of humanized plasma and epithelial lining fluid exposures of meropenem, cefiderocol and tobramycin against a challenge set of Klebsiella pneumoniae and Pseudomonas aeruginosa in a standardized neutropenic murine pneumonia model
Andrew J Fratoni and othersJournal of Antimicrobial Chemotherapy, dkaf100, https://doi.org/10.1093/jac/dkaf100 -
Research Article 26 March 2025
Population pharmacokinetic model of oral minocycline in critically ill adult patients with ventilator-associated pneumonia
Zoe Athanassa and othersJournal of Antimicrobial Chemotherapy, dkaf090, https://doi.org/10.1093/jac/dkaf090 -
Research Article 25 March 2025
Comparing serotype coverage of pneumococcal vaccines with PCV21 (V116), a new 21-valent conjugate pneumococcal vaccine, and the epidemiology of its eight unique Streptococcus pneumoniae serotypes (15A, 15C, 16F, 23A, 23B, 24F, 31 and 35B) causing invasive pneumococcal disease in adult patients in Canada: SAVE study, 2018–21
John J Schellenberg and othersJournal of Antimicrobial Chemotherapy, dkaf085, https://doi.org/10.1093/jac/dkaf085 -
Research Article 25 March 2025
Bactericidal activity of antibiotic combinations against clinical isolates of Enterococcus gallinarum and Enterococcus casseliflavus
David Landman and othersJournal of Antimicrobial Chemotherapy, dkaf095, https://doi.org/10.1093/jac/dkaf095 -
Research Article 25 March 2025
Biannual azithromycin mass drug administration for reduction of childhood mortality: a systematic review and meta-analysis
Meenalotchini Prakash Gurunthalingam and othersJournal of Antimicrobial Chemotherapy, dkaf092, https://doi.org/10.1093/jac/dkaf092 -
Research Article 24 March 2025
A pre-post quasi-experimental study of the impact of TDM-guided aggressive pharmacokinetic/pharmacodynamic target attainment of continuous infusion ceftolozane/tazobactam monotherapy in treating severe Pseudomonas aeruginosa infections: a strategy useful for raising the bar?
Milo Gatti and othersJournal of Antimicrobial Chemotherapy, dkaf098, https://doi.org/10.1093/jac/dkaf098 -
Research Article 24 March 2025
Validation of a modified rapid test to detect the cefazolin inoculum effect in methicillin-susceptible Staphylococcus aureus from bloodstream infections in hospitals from North and Latin America
Sara I Gomez-Villegas and othersJournal of Antimicrobial Chemotherapy, dkaf093, https://doi.org/10.1093/jac/dkaf093 -
Research Article 24 March 2025
Nature-inspired designing of KLR- and KLS-rich antimicrobial peptides: unleashing the antibiofilm potential of RbP12 against MDR S. aureus and P. aeruginosa
Zeeshan Yaseen and othersJournal of Antimicrobial Chemotherapy, dkaf079, https://doi.org/10.1093/jac/dkaf079 -
Research Article 21 March 2025
A retrospective observational cohort study of oral azithromycin treatment for Legionnaires’ disease
Lorna Pairman and othersJournal of Antimicrobial Chemotherapy, dkaf081, https://doi.org/10.1093/jac/dkaf081 -
Research Article 20 March 2025
Utilizing dried blood spot micro-sampling and population pharmacokinetic modelling and simulation to inform ampicillin dosing in Chinese neonates
Jianmei Lv and othersJournal of Antimicrobial Chemotherapy, dkaf091, https://doi.org/10.1093/jac/dkaf091 -
Brief Report 20 March 2025
The tear production of tecovirimat in a single hospitalized mpox patient: a pharmacokinetic analysis
Stephen D Woolley and othersJournal of Antimicrobial Chemotherapy, dkaf071, https://doi.org/10.1093/jac/dkaf071 -
Correction 19 March 2025
Correction to: Linezolid brain penetration in neurointensive care patients
Journal of Antimicrobial Chemotherapy, dkaf099, https://doi.org/10.1093/jac/dkaf099 -
Research Article 19 March 2025
Screening for carbapenemase-producing Enterobacterales (CPE)—considering the practical implications of molecular results, the value of culture and deciding criteria for resistance
Mairead Skally and othersJournal of Antimicrobial Chemotherapy, dkaf088, https://doi.org/10.1093/jac/dkaf088 -
Research Article 19 March 2025
Prophylaxis against Pneumocystis jirovecii pneumonia and toxoplasmosis with low-dose Trimethoprim-sulfamethoxazole (cotrimoxazole 20/100 mg) in heart transplant patients. The PAPTO-LOCO observational comparative study
Dahlia Aggoun and othersJournal of Antimicrobial Chemotherapy, dkaf087, https://doi.org/10.1093/jac/dkaf087 -
Research Article 19 March 2025
Ceftazidime-avibactam plus aztreonam cocktail for the treatment of VIM-producing Pseudomonas aeruginosa infections: good enough to have another?
Manuel Pina-Sánchez and othersJournal of Antimicrobial Chemotherapy, dkaf083, https://doi.org/10.1093/jac/dkaf083 -
Brief Report 19 March 2025
First report of SME-carbapenemase–producing Serratia marcescens in France
Manon Robert and othersJournal of Antimicrobial Chemotherapy, dkaf072, https://doi.org/10.1093/jac/dkaf072 -
Brief Report 18 March 2025
In vitro susceptibility testing of vancomycin-resistant Enterococcus faecium to fosfomycin
Stefano Mancini and othersJournal of Antimicrobial Chemotherapy, dkaf084, https://doi.org/10.1093/jac/dkaf084