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Volume 71, Issue 6, June 2016
APPRECIATION
Professor David Greenwood, 25 August 1935–9 July 2015
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1433–1434, https://doi.org/10.1093/jac/dkw027
Leading article
Behind the scenes of JAC: the British Society for Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1435–1437, https://doi.org/10.1093/jac/dkw128
Tags:
antimicrobials
Reviews
Drug resistance mechanisms and their regulation in non-albicans Candida species
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1438–1450, https://doi.org/10.1093/jac/dkv445
Tags:
antifungal agents, azoles, candida, cell wall, drug resistance
Clinical management of dyslipidaemia associated with combination antiretroviral therapy in HIV-infected patients
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1451–1465, https://doi.org/10.1093/jac/dkv494
ORIGINAL RESEARCH
Genetic environment of the transferable oxazolidinone/phenicol resistance gene optrA in Enterococcus faecalis isolates of human and animal origin
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1466–1473, https://doi.org/10.1093/jac/dkw016
IS1216E elements may play a role in disseminating antimicrobial resistance between Enterococcus faecalis of human and animal origin as the oxazolidinone/phenicol gene optrA and other resistance genes are located on the same conjugative plasmids.
Tags:
chromosomes, dna, enterococcus faecalis, genes, genetics
Co-location of the oxazolidinone resistance genes optrA and cfr on a multiresistance plasmid from Staphylococcus sciuri
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1474–1478, https://doi.org/10.1093/jac/dkw040
Tags:
genes, plasmids, resistance genes, staphylococcus, base sequence
Trends and molecular mechanisms of antimicrobial resistance in clinical staphylococci isolated from companion animals over a 16 year period
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1479–1487, https://doi.org/10.1093/jac/dkw029
Companion animals might act as a reservoir of MRSA and methicillin-resistant Staphylococcus epidermidis between these animals and their owners.
Single amino acid substitution Gly186Val in AdeS restores tigecycline susceptibility of Acinetobacter baumannii
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1488–1492, https://doi.org/10.1093/jac/dkw002
Chromobacterium spp. harbour Ambler class A β-lactamases showing high identity with KPC
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1493–1496, https://doi.org/10.1093/jac/dkw020
High prevalence of international ESBL CTX-M-15-producing Enterobacter cloacae ST114 clone in animals
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1497–1500, https://doi.org/10.1093/jac/dkw006
Approximately two out of three ESBL-producing Enterobacter cloacae from animals were found to belong to potentially high-risk clones from humans raising concerns about the potential for transfer of these bacteria between these animals and humans.
Whole-genome typing and characterization of blaVIM19-harbouring ST383 Klebsiella pneumoniae by PFGE, whole-genome mapping and WGS
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1501–1509, https://doi.org/10.1093/jac/dkw003
Inactivation or inhibition of AcrAB-TolC increases resistance of carbapenemase-producing Enterobacteriaceae to carbapenems
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1510–1519, https://doi.org/10.1093/jac/dkw028
Tags:
antibiotics, carbapenem, enterobacteriaceae, ertapenem, lactams
Simultaneous drug resistance detection and genotyping of Mycobacterium tuberculosis using a low-density hydrogel microarray
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1520–1531, https://doi.org/10.1093/jac/dkw015
Delamanid susceptibility testing of Mycobacterium tuberculosis using the resazurin microtitre assay and the BACTEC™ MGIT™ 960 system
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1532–1539, https://doi.org/10.1093/jac/dkw044
Uptake and levels of the antibiotic berberine in individual dormant and germinating Clostridium difficile and Bacillus cereus spores as measured by laser tweezers Raman spectroscopy
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1540–1546, https://doi.org/10.1093/jac/dkv504
Oligonuclear polypyridylruthenium(II) complexes: selectivity between bacteria and eukaryotic cells
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1547–1555, https://doi.org/10.1093/jac/dkw026
Bactericidal and intracellular activity of β-lactams against Mycobacterium abscessus
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1556–1563, https://doi.org/10.1093/jac/dkw022
Tags:
amikacin, cefoxitin, ceftaroline, imipenem, lactams
Non-susceptibility of Escherichia coli, Klebsiella spp., Pseudomonas spp., Streptococcus pneumoniae and Staphylococcus aureus in the UK: temporal trends in England, Northern Ireland, Scotland and Wales
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1564–1569, https://doi.org/10.1093/jac/dkw018
Statin adjunctive therapy shortens the duration of TB treatment in mice
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1570–1577, https://doi.org/10.1093/jac/dkw014
Tags:
mice, rifampin, simvastatin, statins, tuberculosis
Drug permeation and barrier damage in Leishmania-infected mouse skin
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1578–1585, https://doi.org/10.1093/jac/dkw012
Tags:
leishmania, skin, mice, permeability, paromomycin
A long-acting formulation of the integrase inhibitor raltegravir protects humanized BLT mice from repeated high-dose vaginal HIV challenges
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1586–1596, https://doi.org/10.1093/jac/dkw042
Tags:
hiv, mice, plasma, raltegravir, vagina
Plasma and intracellular ribavirin concentrations are not significantly altered by abacavir in hepatitis C virus-infected patients
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1597–1600, https://doi.org/10.1093/jac/dkw009
Tags:
abacavir, hepatitis c, plasma, ribavirin, viruses
α-Fetoprotein level-dependent early hepatitis B surface antigen decline during entecavir therapy in chronic hepatitis B with hepatitis flare
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1601–1608, https://doi.org/10.1093/jac/dkw019
Pharmacogenetics of unboosted atazanavir in HIV-infected individuals in resource-limited settings: a sub-study of the AIDS Clinical Trials Group (ACTG) PEARLS study (NWCS 342)
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1609–1618, https://doi.org/10.1093/jac/dkw005
Prevalence and dynamics of the K65R drug resistance mutation in HIV-1-infected infants exposed to maternal therapy with lamivudine, zidovudine and either nevirapine or nelfinavir in breast milk
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1619–1626, https://doi.org/10.1093/jac/dkw039
Tags:
drug resistance, hiv, infant, k65r mutation, lamivudine
Soluble endothelial protein C receptor (sEPCR) as an inflammatory biomarker in naive HIV-infected patients during ART
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1627–1631, https://doi.org/10.1093/jac/dkw010
Dolutegravir as maintenance monotherapy: first experiences in HIV-1 patients
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1632–1636, https://doi.org/10.1093/jac/dkw011
Tags:
blood hiv rna, dolutegravir, hiv-1, anti-retroviral agents, hiv
Atazanavir/ritonavir monotherapy: 96 week efficacy, safety and bone mineral density from the MODAt randomized trial
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1637–1642, https://doi.org/10.1093/jac/dkw031
Comparison of equal doses of continuous venovenous haemofiltration and haemodiafiltration on ciprofloxacin population pharmacokinetics in critically ill patients
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1643–1650, https://doi.org/10.1093/jac/dkw043
Piperacillin population pharmacokinetics in critically ill patients with multiple organ dysfunction syndrome receiving continuous venovenous haemodiafiltration: effect of type of dialysis membrane on dosing requirements
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1651–1659, https://doi.org/10.1093/jac/dkv503
Evaluation of the efficacy and tolerance of a short 7 day third-generation cephalosporin treatment in the management of acute pyelonephritis in young women in the emergency department
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1660–1664, https://doi.org/10.1093/jac/dkw021
Are first-generation cephalosporins obsolete? A retrospective, non-inferiority, cohort study comparing empirical therapy with cefazolin versus ceftriaxone for acute pyelonephritis in hospitalized patients
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1665–1671, https://doi.org/10.1093/jac/dkw035
Ertapenem for the treatment of bloodstream infections due to ESBL-producing Enterobacteriaceae: a multinational pre-registered cohort study
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1672–1680, https://doi.org/10.1093/jac/dkv502
Metronidazole in conjunction with penicillin neither prevents recurrence nor enhances recovery from peritonsillar abscess when compared with penicillin alone: a prospective, double-blind, randomized, placebo-controlled trial
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1681–1687, https://doi.org/10.1093/jac/dkw038
Tags:
metronidazole, penicillin, peritonsillar abscess, pharynx, fever
Ertapenem versus piperacillin/tazobactam for diabetic foot infections in China: a Phase 3, multicentre, randomized, double-blind, active-controlled, non-inferiority trial
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1688–1696, https://doi.org/10.1093/jac/dkw004
Extensive antibiotic prescription rate among hospitalized patients in Uganda: but with frequent missed-dose days
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1697–1706, https://doi.org/10.1093/jac/dkw025
Tags:
antibiotics, inpatients
Antibiotic prescribing for children in primary care and adherence to treatment guidelines
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1707–1714, https://doi.org/10.1093/jac/dkw030
Antimicrobial allergy ‘labels’ drive inappropriate antimicrobial prescribing: lessons for stewardship
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1715–1722, https://doi.org/10.1093/jac/dkw008
Trends and patterns of antibiotic consumption in Shanghai municipality, China: a 6 year surveillance with sales records, 2009–14
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1723–1729, https://doi.org/10.1093/jac/dkw013
Tags:
antibiotics, china, surveillance, medical
Research Letters
The resistance gene complement of D4, a multiply antibiotic-resistant ST25 Acinetobacter baumannii isolate, resides in two genomic islands and a plasmid
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1730–1732, https://doi.org/10.1093/jac/dkw041
pHN7A8-related multiresistance plasmids (blaCTX-M-65, fosA3 and rmtB) detected in clinical isolates of Klebsiella pneumoniae from Bolivia: intercontinental plasmid dissemination?
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1732–1734, https://doi.org/10.1093/jac/dkv506
Concomitant and multiclonal dissemination of OXA-48-producing Klebsiella pneumoniae in a Spanish hospital
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1734–1736, https://doi.org/10.1093/jac/dkv505
In vivo emergence of ceftaroline resistance during therapy for MRSA vertebral osteomyelitis
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1736–1738, https://doi.org/10.1093/jac/dkw001
Steady-state pharmacokinetics of oral linezolid suspension in a premature infant with osteomyelitis
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Page 1738, https://doi.org/10.1093/jac/dkv507
Orlistat: weight lost at cost of HIV rebound
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1739–1741, https://doi.org/10.1093/jac/dkw033
Letters to the Editor
Comment on: Resistance gene naming and numbering: is it a new gene or not?
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1742–1743, https://doi.org/10.1093/jac/dkw037
Comment on: Mortality due to blaKPCKlebsiella pneumoniae bacteraemia
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1743–1744, https://doi.org/10.1093/jac/dkw034
Resistance gene naming and numbering: is it a new gene or not?—authors' response
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Page 1743, https://doi.org/10.1093/jac/dkw126
Mortality due to blaKPCKlebsiella pneumoniae bacteraemia—authors' response
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Page 1744, https://doi.org/10.1093/jac/dkw059
Errata
Novel transferable erm(46) determinant responsible for emerging macrolide resistance in Rhodococcus equi
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Page 1746, https://doi.org/10.1093/jac/dkw080
Phase 3 pharmacokinetics and safety study of a posaconazole tablet formulation in patients at risk for invasive fungal disease
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Page 1747, https://doi.org/10.1093/jac/dkw079
Ceftaroline fosamil versus ceftriaxone for the treatment of community-acquired pneumonia: individual patient data meta-analysis of randomized controlled trials
Journal of Antimicrobial Chemotherapy, Volume 71, Issue 6, June 2016, Pages 1748–1749, https://doi.org/10.1093/jac/dkw136
