Retraction: Guanosine Inhibits CD40 Receptor Expression and Function Induced by Cytokines and β Amyloid in Mouse Microglia Cells

We wish to retract the article titled “Guanosine Inhibits CD40 Receptor Expression and Function Induced by Cytokines and β Amyloid in Mouse Microglia Cells” by Iolanda D’Alimonte, Vincenzo Flati, Mariagrazia D’Auro, Elena Toniato, Stefano Martinotti, Michel P. Rathbone, Shucui Jiang, Patrizia Ballerini, Patrizia Di Iorio, Francesco Caciagli, and Renata Ciccarelli, The Journal of Immunology, 2007, 178: 720–731.

A band in Fig. 8C appears to have been reproduced in at least five lanes. Due to a short circuit in the electrical power that irreversibly damaged various devices including PCs for data storage in their laboratories, the authors were unable to produce the original data to refute the concerns of inappropriate manipulation of the data. Nevertheless, the undersigned authors view any manipulation of data as unacceptable and regret that, without the original files, it was not possible to identify the person(s) responsible.

Hence, the article is being retracted with the consent of the authors listed here. Based on other data provided by the authors, the editors are satisfied that the findings reported in the article are nonetheless valid.

Iolanda D’Alimonte

Section of Pharmacology

Department of Experimental and Clinical Sciences

University of Chieti-Pescara

Chieti, Italy

Vincenzo Flati

Department of Biotechnological and Applied Clinical Sciences

University of L'Aquila

L'Aquila, Italy

Elena Toniato

Department of Medical, Oral and Biotechnology Sciences

University of Chieti-Pescara

Chieti, Italy

Stefano Martinotti

Department of Medical, Oral and Biotechnology Sciences

University of Chieti-Pescara

Chieti, Italy

Michel P. Rathbone

Department of Medicine

McMaster University

Hamilton, Ontario, Canada

Shucui Jiang

Departments of Neurosurgery and Neurobiology

McMaster University Medical Centre

Hamilton, Ontario, Canada

Patrizia Di Iorio

Section of Pharmacology

Department of Experimental and Clinical Sciences

University of Chieti-Pescara

Chieti, Italy

Francesco Caciagli

Section of Pharmacology

Department of Experimental and Clinical Sciences

University of Chieti-Pescara

Chieti, Italy

Renata Ciccarelli

Section of Pharmacology

Department of Experimental and Clinical Sciences

University of Chieti-Pescara

Chieti, Italy