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Volume 47, Issue 2
February 2017
ISSN 0368-2811
EISSN 1465-3621
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European Organisation for Research and Treatment of Cancer and Japan Clinical Oncology Group initiated collaboration to facilitate intercontinental clinical trial between Europe and Asia. This collaboration could serve as a model to build more global agenda in cancer clinical trials.

Determining UGT1A1 polymorphisms in ovarian clear cell carcinoma patients can indicate their prognoses after irinotecan treatment.

Reported herein is the effective use of MMF in addition to corticosteroids in order to treat a subject with rapidly developed steroid-refractory severe hepatitis associated with ipilimumab administration.

The colorectal cancer screening program using colonoscopy that was conducted on an island achieved considerably higher participation rate than the conventional screening program using fecal immunochemical test.

In matched cohort, lung cancer patients with and without gastrointestinal tract cancer history demonstrated equivalent outcome. Patients with well-controlled gastrointestinal tract cancer can be included in lung cancer trial.

Solid tumor size on high-resolution computed tomography and the maximum standardized uptake value on F-18-fluorodeoxyglucose positron emission tomography/computed tomography are useful for predicting distant recurrence in patients with clinical Stage IA lung adenocarcinoma after complete resection.

The viral load of HPV58 in precancerous cervical lesions increases gradually with disease progression. A high degree of viral integration may be a risk factor for cervical cancer.

We provide long-term outcome data in patients with primary central nervous system lymphoma. The neurotoxicity and Questionnaire-30 and Brain Cancer Module-20 scores of long-term survivors are also presented.

A multicentre randomised controlled trial protocol comparing extensive intraoperative peritoneal lavage versus standard lavage for patients with cT3/4 stomach cancer undergoing curative resection with overall survival as the primary outcome.

Patients with tongue cancers that are ≥2 mm thick or have muscle invasion have a high risk of neck metastasis, and elective neck dissection should be considered.

This phase 2 study investigated eribulin in previously treated Japanese patients with advanced/metastatic soft tissue sarcoma. Eribulin showed clinical activity together with a manageable safety profile.

The prevalences of Lynch syndrome and Lynch-like syndrome were 0.7% and 0.2%, respectively, among the 1,234 newly diagnosed colorectal cancer patients in Japan, based on the universal screening approach.


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