European Organisation for Research and Treatment of Cancer and Japan Clinical Oncology Group initiated collaboration to facilitate intercontinental clinical trial between Europe and Asia. This collaboration could serve as a model to build more global agenda in cancer clinical trials.
UGT1A1 polymorphism as a prognostic indicator of stage I ovarian clear cell carcinoma patients treated with irinotecan
Determining UGT1A1 polymorphisms in ovarian clear cell carcinoma patients can indicate their prognoses after irinotecan treatment.
Severe hepatitis arising from ipilimumab administration, following melanoma treatment with nivolumab
Reported herein is the effective use of MMF in addition to corticosteroids in order to treat a subject with rapidly developed steroid-refractory severe hepatitis associated with ipilimumab administration.
Regional colorectal cancer screening program using colonoscopy on an island: a prospective Nii-jima study
The colorectal cancer screening program using colonoscopy that was conducted on an island achieved considerably higher participation rate than the conventional screening program using fecal immunochemical test.
Is cancer history really an exclusion criterion for clinical trial of lung cancer? Influence of gastrointestinal tract cancer history on the outcomes of lung cancer surgery
In matched cohort, lung cancer patients with and without gastrointestinal tract cancer history demonstrated equivalent outcome. Patients with well-controlled gastrointestinal tract cancer can be included in lung cancer trial.
Preoperative predictors of distant recurrence in patients with clinical stage IA lung adenocarcinoma undergoing complete resection
Solid tumor size on high-resolution computed tomography and the maximum standardized uptake value on F-18-fluorodeoxyglucose positron emission tomography/computed tomography are useful for predicting distant recurrence in patients with clinical Stage IA lung adenocarcinoma after complete resection.
Viral load and integration status of HPV58 associated with cervical lesion severity in women of Northeast China
The viral load of HPV58 in precancerous cervical lesions increases gradually with disease progression. A high degree of viral integration may be a risk factor for cervical cancer.
We provide long-term outcome data in patients with primary central nervous system lymphoma. The neurotoxicity and Questionnaire-30 and Brain Cancer Module-20 scores of long-term survivors are also presented.
Extensive peritoneal lavage after curative gastrectomy for gastric cancer (EXPEL): study protocol of an international multicentre randomised controlled trial
A multicentre randomised controlled trial protocol comparing extensive intraoperative peritoneal lavage versus standard lavage for patients with cT3/4 stomach cancer undergoing curative resection with overall survival as the primary outcome.
Patients with tongue cancers that are ≥2 mm thick or have muscle invasion have a high risk of neck metastasis, and elective neck dissection should be considered.
Phase 2 study of eribulin in patients with previously treated advanced or metastatic soft tissue sarcoma
This phase 2 study investigated eribulin in previously treated Japanese patients with advanced/metastatic soft tissue sarcoma. Eribulin showed clinical activity together with a manageable safety profile.
Prevalence of Lynch syndrome and Lynch-like syndrome among patients with colorectal cancer in a Japanese hospital-based population
The prevalences of Lynch syndrome and Lynch-like syndrome were 0.7% and 0.2%, respectively, among the 1,234 newly diagnosed colorectal cancer patients in Japan, based on the universal screening approach.