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John A. Stern, George Winokur, David T. Graham, Robert Lefton, Effect of Enforced Activity Stress on the Development of Experimental Papillomas in Mice, JNCI: Journal of the National Cancer Institute, Volume 23, Issue 5, November 1959, Pages 1013–1018, https://doi.org/10.1093/jnci/23.5.1013
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Abstract
The experimental stress of enforced activity was shown to be related to a significant enhancement of papilloma development and death rate. Stress initiated concurrently with application of the carcinogen exerted a more profound effect than was observed in pre-stressed animals.
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