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Hiroshi Kobayashi, Kokichi Kikuchi, Tsuneo Maki, Iwao Nishiya, Two Transplantable Uterine Adenocarcinomas in the Rat, JNCI: Journal of the National Cancer Institute, Volume 34, Issue 1, January 1965, Pages 13–20, https://doi.org/10.1093/jnci/34.1.13
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Summary
Two transplantable uterine adenocarcinomas in rats were studied. Histologically, a periodic acid-Schiff-positive substance produced by the tumor cells accumulated around the cells, and ultramicroscopic examinations revealed the so-called intercellular “lamellar structure.” The sex hormones, estrogen and androgen, were found to be significantly related to the growth of these tumors.
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