Clinical and Hematologic Studies With 1-β-D-Arabinosylcytosine

Papac, Rose J.

doi:10.1093/jnci/40.5.997

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Clinical and Hematologic Studies With 1-β-D-Arabinosylcytosine

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Summary

1-β-D-Arabinosylcytosine is a synthetic nucleosidc with demonstrable tumor-inhibitory effects in human neoplasms. It produces a striking megaloblastosis associated with changes in serum folate and vitamin B₁₂ levels. The pathogenesis of the megaloblastosis in relation to the biochemical effects of the agent is discussed.

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Clinical and Hematologic Studies With 1-β-D-Arabinosylcytosine

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Clinical and Hematologic Studies With 1-β-D-Arabinosylcytosine

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