Spontaneous Gastric Adenocarcinomas of Dogs: A Review

Summary

Gastric adenocarcinomas probably account for fewer than 1% of all malignant neoplasms of dogs, though precise incidence is not known. They are rarely observed in other animals. The canine gastric carcinoma is a uniform histologic entity that corresponds most nearly to the human diffuse histologic type. As in man, the canine carcinoma originates more frequently in the antral segment along the lesser curvature, and the patterns of intragastric infiltration and metastases are the same. Both human and canine gastric carcinomas are more frequent in males, and incidence increases with age. No breed preference has been demonstrated for dogs. Foci of intestinal metaplasia can be demonstrated in stomachs of one-third of dogs with gastric carcinomas.