Herpesvirus saimiri: VII. Induction of Malignant Lymphoma in New Zealand White Rabbits

Daniel, M. D.; Meléndez, L. V.; Hunt, R. D.; King, N. W.; Anver, M.; Fraser, C. E. O.; Barahona, H.; Baggs, Baggs

doi:10.1093/jnci/53.6.1803

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Herpesvirus saimiri: VII. Induction of Malignant Lymphoma in New Zealand White Rabbits

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Summary

Herpesvirus saimiri and squirrel monkey heart isolate, a closely related strain of H. saimiri, induced malignant lymphomas in New Zealand White rabbits in as few as 17 days by a single intravenous inoculation. The duration of the disease in rabbits varied from 17 to 149 days. Both light and electron microscopy revealed a close resemblance between these rabbit lymphomas and H. saimiri-induced lymphomas in monkeys.

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Herpesvirus saimiri: VII. Induction of Malignant Lymphoma in New Zealand White Rabbits

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Herpesvirus saimiri: VII. Induction of Malignant Lymphoma in New Zealand White Rabbits

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