Brief Communication: Minute Chromatin Bodies in a Murine In Vitro Cell Line

de Salum, Sonia B.; Larripa, Irene

doi:10.1093/jnci/55.3.717

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Brief Communication: Minute Chromatin Bodies in a Murine In Vitro Cell Line

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Summary

A murine anaplastic sarcoma and an in vitro cell line established from it were studied by the TG banding technique. The neoplasm originated in a BALB/c mouse inoculated with human tumor cells. Microchromatin bodies were found in 100% of the karyotypes in the original tumor and in the 120 in vitro passages. A long marker chromosome, also observed in all metaphases, was interpreted as a translocation in tandem of a #16 chromosome into a #1; this involved loss of the centromeric part of chromosome #1.

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Brief Communication: Minute Chromatin Bodies in a Murine In Vitro Cell Line

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