Murine Oncornavirus Activation in the Pancreas During Infection With Venezuelan Equine
Encephalitis Virus

Harrison, Alyne K.; Murphy, Frederick A.

doi:10.1093/jnci/55.4.917

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Murine Oncornavirus Activation in the Pancreas During Infection With Venezuelan Equine Encephalitis Virus

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Abstract

Electron microscopic studies of the pancreases of 3-week-old ICR Swiss mice infected with Venezuelan equine encephalitis virus and killed 6 days post inoculation (at which time they were moribund) indicated significantly more type-C particles than were found in uninfected controls. This phenomenon was apparently possible because of the microanatomy of the pancreas, in which interstitial spaces allowed accumulation of virus particles.

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Murine Oncornavirus Activation in the Pancreas During Infection With Venezuelan Equine Encephalitis Virus

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Murine Oncornavirus Activation in the Pancreas During Infection With Venezuelan Equine Encephalitis Virus

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