Lack of Infectivity of Bovine Leukemia (C-Type) Virus to Rats

Barthold, Stephen W.; Baumgartener, Lois E.; Olson, Carl

doi:10.1093/jnci/56.3.643

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Lack of Infectivity of Bovine Leukemia (C-Type) Virus to Rats

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Sprague-Dawley rats were given ip injections of bovine culture and sheep cultures of bovine leukemia virus (BLV) and Gross passage-A leukemia virus [MuLV(G)]. Sera were tested for precipitin antibodies to BLV antigens, but none had antibodies to BLV antigens. BLV did not induce tumors in Sprague-Dawley rats, but the rats were susceptible to MuLV(G) at low doses.

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