Production of Carcinoembryonic Antigen by Human Prostate Epithelial Cells In Vitro

Williams, Richard D.; Bronson, David L.; Elliott, Arthur Y.; Fraley, Elwin E.

doi:10.1093/jnci/58.4.1115

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Production of Carcinoembryonic Antigen by Human Prostate Epithelial Cells In Vitro

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Abstract

The medium from all 16 human prostate epithelial cell cultures tested contained elevated levels of carcinoembryonic antigen (CEA) or CEA-like substance; 11 of 16 had greater than 20 ng CEA/ml. In contrast, medium from cultures of other human tissues (prostate fibroblasts, genitourinary tumors, melanoma, and nontumor tissue), as well as media controls, contained less than 1 ng CEA/ml. Results indicated that CEA determinations may provide a way to identify human prostatic epithelium in culture.

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Production of Carcinoembryonic Antigen by Human Prostate Epithelial Cells In Vitro

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Production of Carcinoembryonic Antigen by Human Prostate Epithelial Cells In Vitro

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