Inhibition of Tumor Growth by the Peptidoglycan From Bacillus megaterium

Nauciel, C.; Goguel, A. F.

doi:10.1093/jnci/59.6.1723

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Inhibition of Tumor Growth by the Peptidoglycan From Bacillus megaterium

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Abstract

When injected in admixture with tumor cells, the peptidoglycan extracted from Bacillus megaterium inhibited the growth of a chemically induced fibrosarcoma in syngeneic rats, In some instances, the tumor growth was totally suppressed. Animals rejecting mixed inocula exhibited a tumor-specific immunity. Peptidoglycan was not cytotoxic for tumor cells; it rendered macrophages nonspecifically cytotoxic.

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Inhibition of Tumor Growth by the Peptidoglycan From Bacillus megaterium

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Inhibition of Tumor Growth by the Peptidoglycan From Bacillus megaterium

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