Responses

Extract

Multiple neoplasias are a clinical reality. The causes are numerous, such as previous chemotherapy and radiotherapy for other malignant tumors, tobacco use, familial syndromes, or possibly diet ( 1 – 3 ).

The purpose of our letter was not to describe freaks of nature but to emphasize that the occurrences of multiple neoplasias in the same patient are becoming more frequent.

We agree with Crocetti and Buiatti that a common classification of multiple neoplasias should be adopted to allow for comparisons among studies.