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Five researchers received the General Motors Cancer Research Foundation Awards in early June.

The Alfred P. Sloan Jr. Prize was awarded to Avram Hershko, M.D., Ph.D., professor of biochemistry, Technion–Israel Institute of Technology; and Alexander J. Varshavsky, Ph.D., professor of cell biology, California Institute of Technology, for the discovery of the ubiquitin system for protein degradation and the crucial functions of this system in cellular regulation. The Sloan Prize honors the most outstanding recent basic science contribution to cancer research.

The Charles F. Kettering Prize was given to Monroe E. Wall, Ph.D., chief scientist, Research Triangle Institute; and Mansukh C. Wani, Ph.D., principal scientist, Research Triangle Institute, for the discovery of two chemotherapeutic compounds—Camptothecin™ and Taxol®. The Kettering Prize recognizes the most outstanding recent contribution to the diagnosis or treatment of cancer.

Bert Vogelstein, M.D., professor of oncology, Johns Hopkins University, Baltimore, received the Charles S. Mott Prize for his role in defining the molecular pathogenesis of colorectal cancer. The Mott Prize honors the most outstanding recent contribution to the discovery of the cause or ultimate prevention of human cancer.

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