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Bryan J Vonasek, Mwawi Nyirongo, Alexander Kondwani, Tiwonge Kamvaunamwali, Doris Ng’oma, Emily J Ciccone, James Kaphatika, Amazing-Grace Tepeka, Mercy Kumwenda, Jens Eickhoff, Anthony J Garcia-Prats, Tisungane Mvalo, Infections and Antibiotic Resistance in Malawian Children Under Five-Years Old Hospitalized With Severe Acute Malnutrition, Journal of the Pediatric Infectious Diseases Society, Volume 14, Issue 1, January 2025, piae120, https://doi.org/10.1093/jpids/piae120
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Abstract
This prospective cohort study from Malawi updates our understanding of the burden of bacterial infections and drug resistance in children <5 years hospitalized with severe acute malnutrition. Urinary tract infection was diagnosed in 20% and bacteremia in 10%. Resistance to first- and second-line antibiotics occurred in >1/3 of the bacteria isolated.