High Prevalence and Increased Severity of Norovirus Mixed Infections Among Children 12–24 Months of Age Living in the Suburban Areas of Lima, Peru

Abstract

In an active diarrhea surveillance study of children aged 12–24 months in Lima, Peru, norovirus was the most common pathogen identified. The percentage of mixed (bacterial and noroviral) infections was significantly higher among norovirus-positive samples (53%) than among norovirus-negative samples (12%). The combination of norovirus with the most common bacterial pathogens was associated with increased clinical severity over that of either single-pathogen norovirus or single-pathogen bacterial infections.