The Journal of Sexual Medicine

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Glucagon-like peptide-1 agonist weight loss medications decrease sexual desire: a theoretical framework based in the serotonergic pathway

Meghan C Tveit and others

In today’s culture, being overweight or obese is contrary to the idealized image of feminine beauty. As a result, individuals often turn to unproven dietary supplements and medications, or FDA-approved weight loss drugs in order to achieve a desired weight/body image. One such class of FDA-approved ...

Latest Articles

Online expressive writing intervention for the psychosexual well-being of women with a history of childhood sexual abuse: a randomized clinical trial

Chelsea D Kilimnik and Cindy M Meston

Background Sexual schema expressive writing that addresses nonconsensual sexual experiences has demonstrated initial support for improving psychosexual well-being for women with childhood sexual abuse (CSA) histories and is easily modifiable to an online modality for accessibility and scalability. ...

Simultaneous perineal urethroplasty and penile prosthesis explantation for urethral stricture and fractured malleable penile prosthesis through a single perineal incision: a case report and literature review

Nazim Furkan Gunay and others

Penile prosthesis implantation (PPI) is a potential treatment option for men with medication-refractory erectile dysfunction (ED) or those with severe ED, based on shared decision-making. Although 3-piece inflatable prostheses are the most commonly used type today, malleable prostheses are also ...

Exploring pain perception and depression in vulvodynia: the role of catastrophizing and pain acceptance

Spinoni Marta and others

Background In the context of vulvodynia, a gynecological disorder characterized by chronic vulvar pain affecting an estimated 10% of women, with significant impacts on sexual health, mental well-being, and productivity, the Common-Sense Model of Illness Self-Regulation, a well-established framework ...

Improved psychosexual wellbeing with administration of combined Sildenafil plus Melatonin compared than either drug alone in management of women with polycystic ovarian syndrome: a 3-month randomized clinical study

Zahra Asadi Kalameh and others

Background Given the significant impact of depression, sexual function, and health-related quality of life (HRQOL) in women with Polycystic Ovarian Syndrome (PCOS), it is crucial to identify scientifically supported interventions that enhance these outcomes and thereby promote HRQOL. Aim The ...

The relationship between perceived stress and erectile function in patients with psychogenic erectile dysfunction: the mediating role of fatigue

Zhi Cao and others

Background Psychological stress is closely linked to psychogenic erectile dysfunction (pED). In our recent clinical work, many pED patients report high levels of stress and fatigue, leading us to hypothesize these factors may play a contributory role in the development of pED. Aim This research ...

Medical malpractice after treatment of Peyronie’s disease

Zachary Boston and others

Background Peyronie’s Disease is a fibrotic tunica albuginea disorder resulting in penile deformity. Aim This analysis provides an important investigation of medical malpractice cases related to the treatment of Peyronie’s Disease. Methods The LexisNexis+ and Westlaw databases were used to access ...

Exploring subjective and genital sexual response in transgender women upon addition of low-dose testosterone to feminizing gender-affirming hormone therapy: a feasibility study

Noor C Gieles and others

Background Transgender women using feminizing gender-affirming hormone therapy who underwent a gonadectomy generally have lower testosterone levels than cisgender women. It is unknown if testosterone supplementation can influence subjective and genital sexual response in transgender women and ...

Impact of female sexual dysfunctions on women undergoing pipelle endometrial biopsy and endocervical curettage for abnormal uterine bleeding: a prospective cross-sectional study

Sevim Baltali and others

Background Endometrial and endocervical biopsy sampling provides critical information for diagnosing and planning treatment in cases of abnormal uterine bleeding or suspected gynecological conditions. However, documented failure rates of up to one-third due to difficulties accessing the uterine ...

Preliminary analysis of the Female Genital Self-Image Scale (FGIS-4) and the Male Genital Self-Image Scale (MGIA-5) in an international sample of adults with spina bifida

Devon J Hensel and others

Introduction Common chronic health conditions associated with spina bifida (SB) may impact sexual health among adults in this population, including genital self-image (GSI), but no studies explore this topic. Aim The primary aim of this study was to provide a preliminary psychometric assessment of ...

Pelvic pain, sexual distress and satisfaction: cross-sectional study

Arife Büşra Karaosmanoğlu and others

Background Pelvic pain significantly increases sexual distress and reduces sexual satisfaction in women. Aim The aim of this study is to identify the factors that influence women’s pelvic pain, sexual distress, and satisfaction. Methods This research was designed as a descriptive cross-sectional ...

Pornography and problematic pornography use: occurrence, patterns, and associated factors in a national gender-based controlled cross-sectional study

Rezvan Zarei and others

Background A study on pornography is vital due to internet accessibility, widespread pornography usage, and a lack of data, especially in non-western countries. Aim This study estimates the occurrence of pornography use (PU), compares demographic, sexual, and psychological factors between users ...

Association of blood biomarkers for neural injury with recent, frequent exposure to partnered sexual strangulation in young adult women

Megan E Huibregtse and others

Background “Choking” or partnered strangulation is an emerging and popular sexual behavior that is more often experienced by young women, yet the neurobiological consequences of partnered sexual strangulation remain unclear. Aim The aim of the present study was to assess differences in 5 ...

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