HP-04-006 Association of Sexual Identity and Activity with Prostate-specific Antigen (PSA) in a Prostate Cancer Screening Population

Extract

Objective

In this study, we investigated the association of sexual identity and activity with PSA.

Methods

Between April 2014 and April 2018, 45-year old men within the German Male Sex-Study were asked, among other things, about their sexual identity (heterosexual, homosexual), practicing anal sex (yes, no), frequency of masturbation and sexual activity in the last 3 months (0, 1, 2-3, >3 per week), and self-rated ejaculation time <2 minutes (yes, no). PSA levels were measured as well.

Results

We included 13,489 men (heterosexual n=13,013, homosexual n=476) in this analysis. The median PSA level was 0.75 ng/ml (ICR: 0.51-1.08 ng/ml, mean: 0.91 ng/ml). Homosexual men had a slightly higher PSA than heterosexual (0.79 ng/ml vs. 0.75 ng/ml). Homosexual men practicing anal sex (61.9%) had a tendency to a higher PSA level compared to homosexual men not practicing anal sex (0.82 ng/ml vs. 0.78 ng/ml). A higher frequency of masturbation or sexual activity was associated with a slightly higher PSA level in the entire study population and in heterosexual and homosexual men. Ejaculation time <2 minutes (9.1%) was associated with a lower PSA level in the entire study population (0.75 ng/ml vs. 0.72 ng/ml), in heterosexual men (0.75 ng/ml vs. 0.72 ng/ml), and in homosexual men (0.80 ng/ml vs. 0.75 ng/ml).