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Journal Article

Ferritin-based biomarkers and their prognostic value in Vietnamese patients with sepsis Get access

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Phung Thanh Huong and others
Laboratory Medicine, lmae112, https://doi.org/10.1093/labmed/lmae112
Published: 06 March 2025
... . Lancet.   2020 ; 395 : 200 - 211 . https://doi.org/ 10.1016/S0140-6736(19)32989-7 2. Karakike   E , Giamarellos-Bourboulis   EJ , Kyprianou   M , et al   Coronavirus disease 2019 as cause of viral sepsis: a systematic review and meta-analysis . Crit Care Med.   2021 ; 49 : 2042...
Journal Article

Is the repeat worth it? Optimizing syndromic panel pathogen detection protocols Get access

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Filipe M Cerqueira and others
Laboratory Medicine, lmae100, https://doi.org/10.1093/labmed/lmae100
Published: 17 December 2024
... - TABLE 4. RP Panels with Discrepant Results Between Initial and Repeat Testing Study ID No. Age Sex Initial positive targets Repeat testing positive targets Antibiotics prescribed? RP2019COL9363N 11 mo F Coronavirus HKU Coronavirus HKU Yes Respiratory syncytial virus...
Journal Article

The roles played by hsa-miR-223-5p and mutations in the S gene of SARS-CoV-2 in COVID-19 Get access

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Zeyad Sadeg Sabbar and others
Laboratory Medicine, Volume 56, Issue 1, January 2025, Pages 55–63, https://doi.org/10.1093/labmed/lmae066
Published: 05 August 2024
... of CCL16, CD25, and hsa-miR-223-5p was calculated using the 2-ΔΔct formula. The COVID-19 pandemic has brought more attention to the field of the pathogenesis of coronaviruses. 1 COVID-19 has been associated with a diverse array of complications affecting multiple organ systems within...
Journal Article

Microbiological profile of long COVID and associated clinical and radiological findings: a prospective cross-sectional study

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Monalisa Dey and others
Laboratory Medicine, Volume 55, Issue 5, September 2024, Pages 595–601, https://doi.org/10.1093/labmed/lmae010
Published: 23 March 2024
... virus (IBV), human respiratory syncytial virus (RSV A/B), human adenoviruses (hAdV), enterovirus (hEV), parechovirus (PeV), human parainfluenza viruses (PIV1-4), human metapneumoviruses (MPV), human bocaviruses (hBoV), human rhinoviruses (RV), 4 coronaviruses (hCoV-229E, hCoV-HKU1, hCoV-NL63, and hCoV...
Journal Article

Clinical management of a patient following a granulocyte transfusion from a donor positive for COVID-19

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Jennifer S Woo and others
Laboratory Medicine, Volume 55, Issue 4, July 2024, Pages 524–527, https://doi.org/10.1093/labmed/lmad118
Published: 09 February 2024
... ( 1 ): e0228622 . doi: 10.1128/spectrum.02286-22 16. Self-Testing at Home or Anywhere . Centers for Disease Control and Prevention. 2023 . Accessed November 10, 2023 . https://www.cdc.gov/coronavirus/2019-ncov/testing/self-testing.html#:~:text=Your%20Test%20Is-,Positive,protect%20others...
Journal Article

IgA is the predominant isotype of anti-β2 glycoprotein I in patients with COVID-19

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Sarra Melayah and others
Laboratory Medicine, Volume 55, Issue 3, May 2024, Pages 373–379, https://doi.org/10.1093/labmed/lmad097
Published: 20 December 2023
... , Zhao S , Yu B , et al. A new coronavirus associated with human respiratory disease in China . Nature. 2020 ; 579 ( 7798 ): 265 - 269 . https://doi.org/10.1038/s41586-020-2008-3 2. Gupta A , Madhavan MV , Sehgal K , et al. Extrapulmonary manifestations of COVID...
Journal Article

Blood usage and wastage at an academic teaching hospital before the initial wave of COVID-19 and during and after its quarantine periods

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Amber Nguyen and others
Laboratory Medicine, Volume 55, Issue 2, March 2024, Pages 198–203, https://doi.org/10.1093/labmed/lmad059
Published: 21 July 2023
... , Basavaraju SV. Impact of the early coronavirus disease 2019 pandemic on blood utilization in the United States: a time-series analysis of data reported to the National Healthcare Safety Network Hemovigilance Module . Transfusion. 2021 ; 61 ( suppl 2 ): S36 - S43 . https://doi.org/10.1111/trf.16451...
Journal Article

Neutrophilic Myeloid-Derived Suppressor Cells and Severity in SARS-CoV-2 Infection

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Mona A Omar and others
Laboratory Medicine, Volume 55, Issue 2, March 2024, Pages 153–161, https://doi.org/10.1093/labmed/lmad050
Published: 23 June 2023
.... Scagnolari C , Pierangeli A , Frasca F , et al. Differential induction of type I and III interferon genes in the upper respiratory tract of patients with coronavirus disease 2019 (COVID-19) . Virus Res . 2021 ; 295 : 198283 . doi: 10.1016/j.virusres.2020.198283 5. Wilk AJ...
Journal Article

Reactogenicity and Peak Anti-RBD-S1 IgG Concentrations in Individuals with No Prior COVID-19 Infection Vaccinated with Different SARS-CoV-2 Vaccines

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Lara Milevoj Kopcinovic and others
Laboratory Medicine, Volume 55, Issue 2, March 2024, Pages 162–168, https://doi.org/10.1093/labmed/lmad044
Published: 09 June 2023
... ( 10262 ): 1595 - 1606 . doi: 10.1016/S0140-6736(20)32137-1 3. World Health Organization (WHO) . WHO Coronavirus (COVID-19) Dashboard . Accessed April 22, 2023 . https://covid19.who.int/ 4. Rotshild V , Hirsh-Raccah B , Miskin I , Muszkat M , Matok I . Comparing...
Journal Article

Metagenomic next-generation sequencing for the identification of infections caused by Gram-negative pathogens and the prediction of antimicrobial resistance

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Yang-Hua Xiao and others
Laboratory Medicine, Volume 55, Issue 1, January 2024, Pages 71–79, https://doi.org/10.1093/labmed/lmad039
Published: 30 May 2023
... . Next-generation sequencing of infectious pathogens . JAMA. 2019 ; 321 : 893 − 894 . doi: 10.1001/jama.2018.21669 18. Xu Y , Kang L , Shen Z , et al. Dynamics of severe acute respiratory syndrome coronavirus 2 genome variants in the feces during convalescence . J Genet...
Journal Article

Comparison of IgG Against COVID-19 Between Postmenopausal and Nonmenopausal Women Vaccinated With Sinopharm Vaccine

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Fariba Nabatchian and others
Laboratory Medicine, Volume 54, Issue 5, September 2023, Pages 502–506, https://doi.org/10.1093/labmed/lmac159
Published: 01 March 2023
...-19 between postmenopausal and nonmenopausal women vaccinated with Sinopharm vaccine. COVID-19 menopause women IgG against COVID-19 vaccine inflammation To date, the world has experienced many outbreaks of coronavirus-related infections, including severe acute respiratory syndrome coronavirus...
Journal Article

Long-Term Dynamic of Anti-TrimericS and Anti-RBD Antibodies in Naive and COVID-19 Recovered mRNA-1273 Vaccine Recipients

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Annick Ocmant and others
Laboratory Medicine, Volume 54, Issue 4, July 2023, Pages 388–391, https://doi.org/10.1093/labmed/lmac127
Published: 09 December 2022
... as the capture antigen. The S1 subunit includes the RBD that interacts with angiotensin-converting enzyme-2 host cell receptor. The assay SARS-CoV-2 IgG II quant (Abbott) was also selected here, since it points to the RBD antigen, one of the most immunogenic regions of the coronavirus and the main target...
Journal Article

Validation of Two Revised, Simplified Criteria for Assessing Sepsis-Associated Disseminated Intravascular Coagulation in ICU Patients with Sepsis-3: A Retrospective Study

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Bin Wang and others
Laboratory Medicine, Volume 54, Issue 3, May 2023, Pages 291–298, https://doi.org/10.1093/labmed/lmac112
Published: 14 October 2022
... , et al. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia . J Thromb Haemost. 2020 ; 18 ( 4 ): 844 – 847 . doi: 10.1111/jth.14768 . 19. Iba T , Umemura Y , Watanabe E , et al. Diagnosis of sepsis-induced...
Journal Article

A New Auto-RPA-Fluorescence Detection Platform for SARS-CoV-2

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Jing Tian and others
Laboratory Medicine, Volume 54, Issue 2, March 2023, Pages 182–189, https://doi.org/10.1093/labmed/lmac093
Published: 06 October 2022
... compared the sequences of the primers with those of other virus genomes (including 7 similar coronaviruses, 2 influenza viruses, and 2 other coronaviruses) using BLAST. We found that the sequences were not similar to most of the viral sequences we chose. The amplification efficiency of different pairs...
Journal Article

Comparison between the Sofia SARS Antigen FIA Test and the PCR Test in Detection of SARS-CoV-2 Infection

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Manca Černila and others
Laboratory Medicine, Volume 54, Issue 2, March 2023, Pages e44–e48, https://doi.org/10.1093/labmed/lmac079
Published: 17 August 2022
... . 2. Laboratory testing for 2019 novel coronavirus (2019-nCoV) in suspected human cases. https://www.who.int/publications-detail-redirect/10665-331501 . Accessed January 14, 2022 . 3. Options for the use of rapid antigen tests for COVID-19 in the EU/EEA - first update. European Centre...
Journal Article

Combined Diagnosis of SARS-CoV-2: Rapid Antigen Detection as an Adjunct to Nucleic Acid Detection

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Xuewen Li and others
Laboratory Medicine, Volume 54, Issue 2, March 2023, Pages e37–e43, https://doi.org/10.1093/labmed/lmac089
Published: 27 July 2022
... method for COVID-19 screening in different populations. RT-PCR COVID-19 Lateral flow immunoassay Early screening Sensitivity Abstract Coronavirus disease 2019 is a serious threat to human life, and early diagnosis and screening can help control the COVID-19 pandemic. The high sensitivity of reverse...
Journal Article

Coping with the COVID-19 Pandemic: How a Master’s in Clinical Laboratory Sciences Program Adapted Through the Modification of Existing Resources

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Carol A Carbonaro and others
Laboratory Medicine, Volume 54, Issue 1, January 2023, Pages e29–e30, https://doi.org/10.1093/labmed/lmac086
Published: 18 July 2022
... College began classes in early July 2019. On March 20, 2020, the governor of New York issued an executive order requiring all nonessential businesses closed and limiting any concentration of individuals outside their home, to prevent the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV...
Journal Article

Evaluation of RT-LAMP Assay for Rapid Detection of SARS-CoV-2

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Ya-Ping Li and others
Laboratory Medicine, Volume 54, Issue 1, January 2023, Pages 56–64, https://doi.org/10.1093/labmed/lmac030
Published: 16 July 2022
... test for coronaviruses in the context of COVID-19 pandemic . Biology . 2020 ; 9 ( 8 ): 182 . 8. Feng W , Newbigging AM , Le C , et al. Molecular diagnosis of COVID-19: challenges and research needs . Anal Chem . 2020 ; 92 ( 15 ): 10196 – 10209 . 9. Lalli MA...
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Forest plots for reverse transcription loop-mediated isothermal amplificati...

Forest plots for reverse transcription loop-mediated isothermal amplificati...

Published: 16 July 2022
Figure 3. Forest plots for reverse transcription loop-mediated isothermal amplification assay for coronavirus disease 2019 of the summary receiver operating characteristic (SROC) curve (A), diagnostic odds ratio (B), sensitivity (C), specificity (D), positive likelihood ratio (E), and negative likelihood
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Forest plots for reverse transcription loop-mediated isothermal amplificati...

Forest plots for reverse transcription loop-mediated isothermal amplificati...

Published: 16 July 2022
Figure 3. Forest plots for reverse transcription loop-mediated isothermal amplification assay for coronavirus disease 2019 of the summary receiver operating characteristic (SROC) curve (A), diagnostic odds ratio (B), sensitivity (C), specificity (D), positive likelihood ratio (E), and negative likelihood