Biofilms are organized masses of microorganisms encased in an extracellular matrix, which is composed of various proteins, DNA, and different carbohydrate polymers. Biofilms occur in nature, in industrial applications of microorganisms and during infection. Fungal biofilms are important in various infections, such as catheter-related candidemia, joint replacement and in pulmonary cystic fibrosis. The formation of a biofilm imparts resistance to drugs and sequestration of the organisms from the immune response. We present here recent papers published in Medical Mycology that highlight the importance of fungal biofilms and examine changes that occur when the fungi are in a biofilm either alone or as a polymicrobic biofilm.
Karl V. Clemons, PhD
Editor in Chief