Although a primary objective of our journal is to publish high quality original research papers, MHR is committed to providing the reproductive community and beyond with insights into subjects as a whole. We have done this, for example, by presenting specific themes and special issues [recently series on Sperm competition (Ramm, 2014) and Mitochondria (St. John, 2015)]. This issue of MHR examines the potential impact of technological breakthroughs. Specifically, it focuses on the challenges and tremendous opportunities brought forward by the use of new methods to study early development.

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Boiani and Cibelli (2016) provide an introduction to this special issue focused on single cell analysis in development. However, this is no ordinary introduction but a detailed and comprehensive...

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