Spine Metastases: From Radiotherapy, Surgery, to Radiosurgery

Spine metastases, Spinal cord compression, Spine radiosurgery, Minimally invasive spine surgery

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Malignancy involving the spine is an important clinical problem in oncology. Secondary malignancy of the spinal column is extremely common. In a study of 2000 patients with bony metastases, nearly 70% were found to have vertebral body metastases.1 There are >180 000 new cases of spinal metastases diagnosed in North America each year, with 20 000 clinical cases of spinal cord compression.2–4 Furthermore, the incidence and prevalence of spine metastases are expected to rise in the future.

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The treatment of metastatic spine disease has evolved significantly in the past decade with the introduction of advances in both surgical and radiation techniques.5 The successful treatment of spine metastases accomplishes effective pain palliation, maintenance or recovery of neurological function and ambulation, local durable pain...