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Life Science

Reviews


Apoptosome and inflammasome: conserved machineries for caspase activation
Jijie Chai and Yigong Shi

Non-coding RNA: a new frontier in regulatory biology
Xiang-Dong Fu

PIWI proteins and their interactors in piRNA biogenesis, germline development and gene expression
Hsueh-Yen Ku and Haifan Lin

Non-coding RNAs and DNA methylation in plants
Yuanyuan Zhao and Xuemei Chen

The endeavor of total synthesis and its impact on chemistry, biology and medicine
K. C. Nicolaou and Christopher R. H. Hale

Molecular dissection of complex agronomic traits of rice: a team effort by Chinese scientists in recent years
Jianru Zuo and Jiayang Li

The hepatitis B virus-associated tumor microenvironment in hepatocellular carcinoma
Pengyuan Yang, Geoffrey J. Markowitz and Xiao-Fan Wang


The Weng’an biota and the Ediacaran radiation of multicellular eukaryotes
Shuhai Xiao, A. D. Muscente, Lei Chen, Chuanming Zhou,James D. Schiffbauer, Andrew D. Wood, Nicholas F. Polys, and Xunlai Yuan

Mesozoic mammals of China: implications for phylogeny and early evolution of mammals
Jin Meng

The Jehol Biota, an Early Cretaceous terrestrial Lagerstätte: new discoveries and implications
Zhonghe Zhou

Cell-SELEX-based aptamer-conjugated nanomaterials for cancer diagnosis and therapy
Hong-Min Meng, Ting Fu, Xiao-Bing Zhang and Weihong Tan

Novel applications of statins for bone regeneration
Sarita R. Shah, Caroline A. Werlang, F. Kurtis Kasper, and Antonios G. Mikos

Etiology, pathogenesis, antivirals and vaccines of hand, foot, and mouth disease
Xiaobo Lei, Sheng Cui, Zhendong Zhao, and Jianwei Wang

Hepatitis C virus vaccine development: old challenges and new opportunities
Dapeng Li, Zhong Huang, and Jin Zhong

New insights into hepatitis B virus biology and implications for novel antiviral strategies
Jieliang Chen, Min Wu, Kuancheng Liu, Wen Zhang, Yaming Li, Xiaohui Zhou, Lu Bai, and Zhenghong Yuan

Oxidative DNA demethylation mediated by Tet enzymes
Guo-Liang Xu and Jiemin Wong

Perspective


Whereto the mega brain projects?
Mu-ming Poo

Ovarian follicles shed new light on dinosaur reproduction during the transition towards birds
Jingmai K. O’Connor, Xiaoting Zheng, Xiaoli Wang, Yan Wang and Zhonghe Zhou

The globalization of messenger RNA regulation
Jack D. Keene

Non-coding RNAs as potent tools for crop improvement
Renyi Liu and Jian-Kang Zhu

Scanning the horizon for nascent environmental hazards
Zhigang Jiang and Keping Ma

Visualizing a protein’s sugars
Chuan He

Bone gain and loss: insights from genomes and fossils
Min Zhu

The end-Permian mass extinction: a still unexplained catastrophe
Shu-zhong Shen, and Samuel A. Bowring

The diversity and host associations of Mesozoic giant fleas
Diying Huang

Fine-tuning MAVS- and STING-mediated antiviral innate immunity
Xingguang Liu and Xuetao Cao

CD8+ cytotoxic T lymphocytes in human influenza virus infection
Tao Dong

New targets for controlling Ebola virus disease
F. Xiao-Feng Qin, Cheng-Yu Jiang, Taijiao Jiang, and Genhong Cheng

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