This article traces public opinion toward tobacco use and anti-smoking legislation over time. Public views on the health effects of tobacco use have changed such that now a majority of individuals believe that smoking and secondhand smoke are harmful. While the public tends to blame the smoker for health problems, there is strong support for restrictions on tobacco advertising, although support is lower in tobacco-producing states. Generally, the public has become more supportive of smoking restrictions in various public domains, although there are important differences across states depending on tobacco production. Evidence suggests that trends in opinion toward tobacco use and anti-smoking legislation have coincided with the decline in smoking prevalence and the increase in anti-smoking policies and public health awareness reports at the federal, state, and local levels.