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Comment on: Survival and associated comorbidities in inclusion body myositis
Maria I Zervou et al.
Comment on: Survival and associated comorbidities in inclusion body myositis: Reply
Elie Naddaf
Health inequalities across patients with early inflammatory arthritis of different ethnicities: what could be the driving factors?
Sytske Anne Bergstra
Anti-CD74 IgA antibodies show diagnostic potential for axial spondyloarthritis but are not associated with microscopic gut inflammation
Ann-Sophie De Craemer et al.
Objectives Gut inflammation commonly occurs in axial spondyloarthritis (axSpA), and is linked to disease activity and outcome. Given the role of IgA in mucosal immunity, we explored the association between anti-CD74 IgA antibodies, gut inflammation and axSpA. Methods Anti-CD74 IgA was measured by ...
Inhibition of calcium/calmodulin-dependent protein kinase IV in arthritis: Dual effect on Th17 cell activation and osteoclastogenesis
Tomohiro Koga et al.
Objective To investigate the role of calcium/calmodulin-dependent protein kinase IV (CaMK4) in the development of joint injury in a mouse model of arthritis and patients with rheumatoid arthritis (RA). Methods Camk4 -deficient, Camk4 flox/flox Lck -Cre, and mice treated with CaMK4 inhibitor KN-93 ...
Management of foot health in people with inflammatory arthritis: British Society for Rheumatology guideline scope
Lara S Chapman et al.
NICE has accredited the process used by BSR to create its clinical guidelines. The term began on 27 February 2012 and the current renewed accreditation is valid until 28 January 2023. More information on accreditation can be viewed at www.nice.org.uk/accreditation . The guideline will be ...
Peripheral expansion of myeloid derived suppressor cells is related to disease activity and damage accrual in inflammatory myopathies
Jiram Torres-Ruiz et al.
Objective Assess the proportion of myeloid derived suppressor cells (MDSC), their expression of arginase-1 and PD-L1, and their relationship with the clinical phenotype of patients with idiopathic inflammatory myopathies (IIM). Methods We recruited 37 IIM adult patients and 10 healthy donors in ...
Outcomes of children born to mothers with systemic lupus erythematosus exposed to hydroxychloroquine or azathioprine
John A Reynolds et al.
Objectives Hydroxychloroquine (HCQ) and azathioprine (AZA) are used to control disease activity and reduce risk of flare during pregnancy in patients with SLE. The aim of this study was to determine outcomes of children born to mothers with SLE exposed to HCQ or AZA during pregnancy and ...
Guselkumab provides sustained domain-specific and comprehensive efficacy using composite indices in patients with active psoriatic arthritis
Laura C Coates et al.
Objectives Evaluate the efficacy of guselkumab for the treatment of active psoriatic arthritis (PsA) utilizing composite indices. Methods Data were pooled from the Phase 3 DISCOVER-1 ( N = 381) and DISCOVER-2 ( N = 739) studies. In both studies, patients were randomized 1:1:1 to subcutaneous ...
Genetic contributions to female gout and hyperuricemia using genome-wide association study and polygenic risk score analyses
Chien-Yu Lin et al.
OBJECTIVES To identify genetic variants and polygenic risk score (PRS) relating to female gout and asymptomatic hyperuricemia (AH) in a genome-wide association study (GWAS). METHODS Gout, AH and normouricemia controls were included from Taiwan biobank and China Medical University Hospital. All ...

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Dr Marwan Bukhari talks to Dr Edward Vital on his Michael Mason prize-winning presentation

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Editor-in-Chief Dr Marwan Bukhari speaks to Rheumatology Co-Editor Prof Ernest Choy about JAK inhibitors to treat RA.

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