Pregnancy triggers the onset of anti-transcriptional intermediary factor 1γ antibody-positive dermatomyositis: a case series

Rheumatology key message

• The onset anti-TIF1γ antibody-positive DM might be triggered by pregnancy in young adult female patients.

Sir, DM is an idiopathic inflammatory myopathy that has been proved to be related to some types of myositis-specific autoantibodies. Several environmental risk factors for the development of DM have been reported. For instance, anti-transcriptional intermediary factor 1 (TIF1)γ antibody is closely associated with paraneoplastic DM in elderly patients [1], whereas a few previous case reports have suggested that pregnancy can trigger the onset of DM in some cases [2]. Akalin etal. [2] reported in their literature review that...