JUVENILE IDIOPATHIC ARTHRITIS-ASSOCIATED UVEITIS: A STUDY OF 69 CASES

citation ID: keac496.032 36 JUVENILE IDIOPATHIC ARTHRITIS-ASSOCIATED UVEITIS: A STUDY OF 69 CASES Djohra Hadef , Samy Slimani, Mohamed Choukri Khamari, Walid Mekaoussi, Alexandre Belot and Pierre Quartier Department of Pediatrics, University Hospital Center of Batna, Faculty of Medicine, Batna 2 University, Atlas Clinic of Rheumatology, Private Clinic of Rheumatology, Batna, Algeria, Pediatric Nephrology, Rheumatology, Dermatology Unit, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, National Referee Centre for Rheumatic and AutoImmune and Systemic diseases in children (RAISE), Lyon, France, Pediatric Immunology-Hematology and Rheumatology Unit Necker Hospital, Assistance Publique Hôpitaux de Paris, National Referee Centre for Rheumatic and AutoImmune and Systemic Diseases in Children (RAISE), Paris,


Background
Juvenile Idiopathic Arthritis (JIA) is the most common rheumatic disease association with uveitis in children.Uveitis is a significant cause of visual morbidity in children with JIA.Geographical variations in the incidence of uveitis in JIA have been reported around the world.

Objectives
The aim of this study was to determine the prevalence of JIA associated uveitis and its features in Batna -Algeria-and to compare the findings with other JIA populations worldwide.Methods A multicentre retrospective descriptive study was conducted in Batna health centers (public and private sectors), over a seven-year period from January 2013 to December 2019, based on data collected on JIA patients.As public sector source, we referred to the department of pediatrics of the university hospital center (CHU Benflis Touhami Batna), and as private sector source, we referred to private adult rheumatologists based in Batna.The studied variables were: gender, age at the initial symptoms, age at diagnosis, JIA subtype based on International League of Associations for Rheumatology (ILAR) criteria, symptoms at onset, disease duration at the latest follow up, presence of uveitis, auto antibodies (antinuclear antibodies, Rheumatoid Factor and anti-CCP) pattern, joint imaging results, JIA medications, JIA status at the time of enrolment and the latest follow-up.

Conclusion
The observed phenotypic variabilities in JIA associated uveitis underscore the existence of true diversities in disease characteristics across geographical areas.Prospective multicentre studies are necessary to better identify the JIA associated uveitis peculiarities in our country.Disclosure of Interest: None declared Background Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in childhood.There is a disparity in the prevalence of Juvenile idiopathic arthritis (JIA) subsets between different geographical areas or ethnic groups.In Arabic and African populations, data describing JIA are scarce.However, the epidemiological studies remain the best tool to understand the disease and to improve its management.Objectives To determine subtype, frequency, demographic and clinical features of JIA in Batna -Algeria-and to compare the findings with other JIA populations worldwide.Methods A multicentre retrospective descriptive study was conducted in Batna health centers (public and private sectors), over a seven-year period from January 2013 to December 2019, based on data collected on JIA patients.As public sector source, we referred to the department of pediatrics of the university hospital center (CHU Benflis Touhami Batna), and as private sector source, we referred to private adult rheumatologists based in Batna.The studied variables were: gender, age at the initial symptoms, age at diagnosis, JIA subtype based on International League of Associations for Rheumatology (ILAR) criteria, symptoms at onset, disease duration at the latest follow up, presence of uveitis, auto antibodies (antinuclear antibodies, Rheumatoid Factor and anti-CCP) pattern, joint imaging results, JIA status at the time of enrolment and the latest follow-up.

Conclusion
Oligoarthritis was the most common JIA subtype in our study.The RF positive polyarthritis frequency was higher than in literature.Prospective multicentre studies are necessary to better identify the JIA peculiarities in our country.

Background
Spondyloarthritis is a heterogeneous group of chronic inflammatory rheumatism, of which enthesitis is the most common.Achilles involvement is frequent and can be disabling, resisting various treatments (non-steroidal anti-inflammatory drugs and local treatment).Only anti TNF alpha drugs are effective.We report the case of a patient with extremely painful achilles enthesitis causing functional disability who responded dramatically to anti TNF alpha.Observation Child A.N, 13 years old, followed for juvenile idiopathic arthritis in the form of psoriatic arthritis evolving since the age of 4 years, treated with methotrexate at a rate of 7.5 mg/week, well balanced for 7 years.Three years later, the patient consulted us for disabling right inflammatory heel pain with the impossibility of putting his shoes on.The clinical examination revealed a painless position with the inability to put the heel on the ground; difficulty in walking requiring the use of ii14 E POSTERS Disclosure of Interest: None declared