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Background The C-reactive protein-triglyceride glucose index (CTI) is a recently introduced index designed to simultaneously assess inflammation (via CRP) and insulin resistance (via the triglyceride-glucose index, TyG), both of which are recognized risk factors for declining testosterone levels in ...
Background Aesthetic procedures for penile enhancement, such as the Penuma silicone sleeve implant, have gained increasing attention for addressing concerns like perceived size, buried or retractile penis, and mild curvature. Aim To assess the online search interest over time for penile enhancement ...
Background Transgender and gender diverse individuals (TGDIs) are people whose gender identity is not in line with their sex assigned at birth, but current surveys used for cisgender patients addressing sexual satisfaction and function (SFS) do not fit the needs of this unique population. Aim The ...
Background Inconsistencies in the Female Sexual Function Index (FSFI) factor structure and current research and clinical guidelines highlight the need for continued exploration of its psychometric evidence. Furthermore, only one study has assessed its measurement invariance (MI), while the only ...
Background The poor clinical situation of type 2 diabetes-induced erectile dysfunction (T2DMED) creates an urgent need for new therapeutic targets. Aim To reveal the conserved molecular mechanism of T2DMED across species. Methods T2DMED rat and mouse models were constructed to extract mRNA from ...
Background Fluctuation in sex hormones and the occurrence of sleep disturbance are 2 major health challenges among midlife women. However, the temporal relationship between them remains unclear. Methods This study included 2488 females (mean ± SD age, 49.0 ± 2.70 years) with an average follow-up of ...
Introduction Persistent genital arousal disorder/genito-pelvic dysesthesia (PGAD/GPD) is a debilitating, but poorly understood disorder. To address the lack of knowledge regarding mechanism and treatments, the International Society for the Study of Women’s Sexual Health (ISSWSH) consensus statement ...
Background The hormonal composition of amniotic fluid during prenatal development, particularly the androgen-to-estrogen ratio, may influence neuronal differentiation related to sexual response patterns and the capacity to control impulsive sexual behaviors in later life. Aim This study aims to ...
Background Patients with schizophrenia frequently encounter challenges related to sexuality and intimacy; however, the underlying causes of these difficulties remain unknown and unexplored. Aim This narrative review aims to explore how the biological/hormonal and psychological/behavioral ...
Background Erectile dysfunction (ED) is a prevalent condition with significant psychological and physiological impacts. Recently, a new concept called movement-based behaviors (MBB) has been proposed, which includes four types of PA: vigorous PA (VPA), moderate-intensity PA (MPA), walking/cycling, ...
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