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The Dryad Digital Repository Special Collection

The Dryad Digital Repository is a curated resource that makes the data underlying scientific publications, like Toxicological Sciences, discoverable, freely reusable, and citable. Toxicological Science’s Editor-in-Chief has curated a special collection of articles on this important, emerging resource.

Subfunctionalization of Paralogous Aryl Hydrocarbon Receptors from the Frog Xenopus Laevis: Distinct Target Genes and Differential Responses to Specific Agonists in a Single Cell Type
Scott H. Freeburg, Eric Engelbrecht, and Wade H. Powell

Dryad in the UK and USA—Prospective and Retrospective Data Publication

Kursheed Khan and Andrew Weeks

Editor’s Highlight: Neonatal Activation of the Xenobiotic-Sensors PXR and CAR Results in Acute and Persistent Down-regulation of PPARα-Signaling in Mouse Liver
Cindy Yanfei Li, Sunny Lihua Cheng, Theo K. Bammler and Julia Yue Cui

Identification of the Additional Mitochondrial Liabilities of 2-Hydroxyflutamide When Compared With its Parent Compound, Flutamide in HepG2 Cells
Amy L. Ball, Laleh Kamalian, Ana Alfirevic, Jonathan J. Lyon and Amy E. Chadwick

Vesicular Monoamine Transporter 2 (VMAT2) Level Regulates MPTP Vulnerability and Clearance of Excess Dopamine in Mouse Striatal Terminals
Kelly M. Lohr, Merry Chen, Carlie A. Hoffman, et. al

More than Manuscripts: Reproducibility, Rigor, and Research Productivity in the Big Data Era
Lance A. Waller and Gary W. Miller

Making Data Accessible: The Dryad Experience

Gary W. Miller

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