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Stefanie Knopp, Dominik Glinz, Laura Rinaldi, Khalfan A. Mohammed, Eliézer K. N'Goran, J. Russell Stothard, Hanspeter Marti, Giuseppe Cringoli, David Rollinson, Jürg Utzinger; FLOTAC: A promising technique for detecting helminth eggs in human faeces, Transactions of The Royal Society of Tropical Medicine and Hygiene, Volume 103, Issue 12, 1 December 2009, Pages 1190–1194, https://doi.org/10.1016/j.trstmh.2009.05.012
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Summary
There is a tendency to neglect diagnostic issues in the era of ‘preventive chemotherapy’ in human helminthiases. However, accurate diagnosis cannot be overemphasized for adequate patient management and monitoring of community-based control programmes. Implicit is a diagnostic dilemma: the more effective interventions are in reducing helminth egg excretion, the less sensitive direct parasitological tests become. Here, experiences gained thus far with the FLOTAC technique for diagnosing common soil-transmitted helminth infections are summarized. A single FLOTAC has higher sensitivity than multiple Kato–Katz thick smears in detecting low-intensity infections. Further validation of the FLOTAC technique in different epidemiological settings is warranted, including diagnosis of intestinal schistosomiasis and food-borne trematodiases.

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