A study was conducted among 552 health workers at 6 health facilities in Nigeria. Lassa virus immunoglobulin (Ig) G antibody was detected in 12 · 3%, using an enzyme-linked immunosorbent assay. Antibody prevalence in the 6 health centres ranged from 1 · 2% to 27 · 3%. Prevalences were higher in primary and secondary health facilities than in tertiary centres. Seroprevalences ranged from 1 · 7% to 23 · 7% among different occupational groups of health workers; the highest observed antibody prevalence was among ward aids. Lassa virus IgM antibody, indicating recent infection, was present in 6 of the health workers, 5 of whom were ward aids and one was a nurse. All of the health workers with specific IgM came from a single facility in Lafia, sampled during an outbreak of Lassa fever.

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