Table 1. Open in new tab Results for...

Table 1.

Results for rs2286885 in the discovery and replication studies

Cohort	Number of subjects^a	Frequency^b	β^b	SE	P-value
TwinsUK (discovery study)	2772	0.55	0.56	0.101	3.48 × 10⁻⁸
BATS	1152	0.53	0.147	0.13	0.2602
BMES	1667	0.55	0.0384	0.099	0.6994
ERF	2589	0.57	0.064	0.089	0.476
Framingham	2455	0.54	0.090	0.091	0.327
GHS1	2727	0.56	0.136	0.078	0.081
GHS2	1130	0.55	−0.020	0.113	0.858
ORCADES	474	0.54	0.358	0.184	0.051
RSIII	2034	0.57	0.057	0.092	0.537
RSII	2116	0.56	0.066	0.094	0.483
RSI	5782	0.57	0.101	0.062	0.106
Southampton	166	0.55	0.042	0.492	0.932
TEST	663	0.53	0.010	0.194	0.960

Cohort	Number of subjects^a	Frequency^b	β^b	SE	P-value
TwinsUK (discovery study)	2772	0.55	0.56	0.101	3.48 × 10⁻⁸
BATS	1152	0.53	0.147	0.13	0.2602
BMES	1667	0.55	0.0384	0.099	0.6994
ERF	2589	0.57	0.064	0.089	0.476
Framingham	2455	0.54	0.090	0.091	0.327
GHS1	2727	0.56	0.136	0.078	0.081
GHS2	1130	0.55	−0.020	0.113	0.858
ORCADES	474	0.54	0.358	0.184	0.051
RSIII	2034	0.57	0.057	0.092	0.537
RSII	2116	0.56	0.066	0.094	0.483
RSI	5782	0.57	0.101	0.062	0.106
Southampton	166	0.55	0.042	0.492	0.932
TEST	663	0.53	0.010	0.194	0.960

BATS, Brisbane Adolescent Twin Study; BMES, Blue Mountains Eye Study; ERF, Erasmus Rucphen Family Study; GHS, Guttenberg Health Study; ORCADES, Orkney Complex Disease Study; RS, Rotterdam Study; TEST, Tasmanian Eye Study of Twins; SE, dtandard error.

^aNumber of subjects refers to those with genotype information for rs2286885.

^bFrequency and beta refer to the frequency and the effect size respectively for the A allele of rs2286885.

This Feature Is Available To Subscribers Only