Distribution of Immunoglobulin M–Specific Trypomastigote Excretory Secretory Antigen Blot Band Patterns, by Micromethod (MM) and Polymerase Chain Reaction (PCR) Results, in Specimens Obtained at Birth From Newborns of Seropositive Mothers
Bands, No. . | Bands Present . | Bands, No. (%), by qPCR and MMa Result . | |||
---|---|---|---|---|---|
qPCR . | MM . | ||||
Negative . | Positive . | Negative . | Positive . | ||
0 | None | 534 (94) | 5 (20) | 388 (90) | 1 (8) |
2 | 1 + 2 | 15 (3) | 0 (0) | 15 (3) | 0 (0) |
3 | 1 + 2 + 3 | 3 (1) | 0 (0) | 3 (1) | 0 (0) |
4 | 1 + 2 + 3 + 4 | 5 (1) | 5 (20) | 7 (2) | 3 (25) |
6 | 1 + 2 + 3 + 4 + 5 + 6 | 10 (2) | 15 (60) | 17 (4) | 8 (67) |
Total | … | 567 | 25 | 430 | 12 |
Pb | <.0001 | <.0001 |
Bands, No. . | Bands Present . | Bands, No. (%), by qPCR and MMa Result . | |||
---|---|---|---|---|---|
qPCR . | MM . | ||||
Negative . | Positive . | Negative . | Positive . | ||
0 | None | 534 (94) | 5 (20) | 388 (90) | 1 (8) |
2 | 1 + 2 | 15 (3) | 0 (0) | 15 (3) | 0 (0) |
3 | 1 + 2 + 3 | 3 (1) | 0 (0) | 3 (1) | 0 (0) |
4 | 1 + 2 + 3 + 4 | 5 (1) | 5 (20) | 7 (2) | 3 (25) |
6 | 1 + 2 + 3 + 4 + 5 + 6 | 10 (2) | 15 (60) | 17 (4) | 8 (67) |
Total | … | 567 | 25 | 430 | 12 |
Pb | <.0001 | <.0001 |
aIn 12 infants with positive results of the micromethod assay, 92% (95% confidence interval, 56%–99%) had either 4 or 6 bands.
bBy the Fisher exact test.
Distribution of Immunoglobulin M–Specific Trypomastigote Excretory Secretory Antigen Blot Band Patterns, by Micromethod (MM) and Polymerase Chain Reaction (PCR) Results, in Specimens Obtained at Birth From Newborns of Seropositive Mothers
Bands, No. . | Bands Present . | Bands, No. (%), by qPCR and MMa Result . | |||
---|---|---|---|---|---|
qPCR . | MM . | ||||
Negative . | Positive . | Negative . | Positive . | ||
0 | None | 534 (94) | 5 (20) | 388 (90) | 1 (8) |
2 | 1 + 2 | 15 (3) | 0 (0) | 15 (3) | 0 (0) |
3 | 1 + 2 + 3 | 3 (1) | 0 (0) | 3 (1) | 0 (0) |
4 | 1 + 2 + 3 + 4 | 5 (1) | 5 (20) | 7 (2) | 3 (25) |
6 | 1 + 2 + 3 + 4 + 5 + 6 | 10 (2) | 15 (60) | 17 (4) | 8 (67) |
Total | … | 567 | 25 | 430 | 12 |
Pb | <.0001 | <.0001 |
Bands, No. . | Bands Present . | Bands, No. (%), by qPCR and MMa Result . | |||
---|---|---|---|---|---|
qPCR . | MM . | ||||
Negative . | Positive . | Negative . | Positive . | ||
0 | None | 534 (94) | 5 (20) | 388 (90) | 1 (8) |
2 | 1 + 2 | 15 (3) | 0 (0) | 15 (3) | 0 (0) |
3 | 1 + 2 + 3 | 3 (1) | 0 (0) | 3 (1) | 0 (0) |
4 | 1 + 2 + 3 + 4 | 5 (1) | 5 (20) | 7 (2) | 3 (25) |
6 | 1 + 2 + 3 + 4 + 5 + 6 | 10 (2) | 15 (60) | 17 (4) | 8 (67) |
Total | … | 567 | 25 | 430 | 12 |
Pb | <.0001 | <.0001 |
aIn 12 infants with positive results of the micromethod assay, 92% (95% confidence interval, 56%–99%) had either 4 or 6 bands.
bBy the Fisher exact test.
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