Interestingly, the analysis of upregulated genes also identified GO categories related to cytokinesis. Two upregulated genes were involved in callose synthesis during cell plate formation: ENDOXYLOGLUCAN TRANSFERASE (DECOY) and CALLOSE SYNTHASE1, both of which are implicated in cell wall/cell plate formation (Table 3   ). Furthermore, the SIAMESE (SIM) gene, with a function in endoreduplication during trichome formation on leaves, and the E2F dimerization partner (DPa) transcription factor gene were upregulated (Table 3). Finally, some overexpressed genes in hub1-1 were related to meristem development, such as the homeodomain genes KNOTTED1-LIKE2 (KNAT2), KNAT6, SHOOT MERISTEMLESS, and 12 NO APICAL MERISTEM genes (Table 3). A total of 13 homeotic genes had an altered expression in hub1-1, among which were two SNF2 proteins (At3g63950 and At1g05480) and a BRAHMA-like protein (At3g06010) of the Polycomb group of proteins in fruitfly (Drosophila melanogaster). Other categories downregulated in hub1-1 comprised genes involved in carboxylic acid metabolism, fatty acid metabolism, lipid biosynthesis, vitamin biosynthesis, cofactor biosynthesis, chlorophyll biosynthesis, transfer RNA metabolism, photosynthesis, and protein targeted to chloroplast (Figure 5   ). Biological processes, such as response to stress, proton transport, cell redox homeostasis, hexose metabolism, cellular respiration, and cofactor catabolism, were significantly overexpressed in hub1-1. Thus, besides effects on meristem development and cell cycle control, the hub1-1 mutant was generally defective in plant metabolism at the transcriptional level, possibly reflecting secondary effects on the observed growth defects.