Endoscopic and histologic outcomes attained by study population at week 12 and one year.
| . | All participants (n = 71) . | Adalimumab induction only/placebo (n = 31) . | Adalimumab (n = 40) . |
|---|---|---|---|
| Ileum GHAS score at week 12, mean (SD) | 3.2 (2.8) | 3.8 (3.0) | 2.7 (2.6) |
| SES-CD score in ileum at week 12, mean (SD) | 3.7 (3.0) | 5.1 (3.0) | 2.4 (2.4) |
| SES-CD score in ileum at one year, mean (SD) | 3.9 (3.3) | 4.3 (4.0) | 3.5 (2.5) |
| Ileum GHAS score at one year, mean (SD) | 2.7 (3.3) | 2.8 (3.2) | 2.6 (3.4) |
| Endoscopic remission of ileum at week 12, n (%) | 9 (12.7) | 2 (6.5) | 7 (17.5) |
| Endoscopic remission of ileum at one year, n (%) | 12 (16.9) | 7 (22.6) | 5 (12.5) |
| Histologic remission of ileum at week 12, n (%)a | 18 (25.4) | 7 (22.6) | 11 (27.4) |
| Histologic remission of ileum at one year, n (%)a | 26 (36.6) | 11 (35.5) | 15 (37.5) |
| . | All participants (n = 71) . | Adalimumab induction only/placebo (n = 31) . | Adalimumab (n = 40) . |
|---|---|---|---|
| Ileum GHAS score at week 12, mean (SD) | 3.2 (2.8) | 3.8 (3.0) | 2.7 (2.6) |
| SES-CD score in ileum at week 12, mean (SD) | 3.7 (3.0) | 5.1 (3.0) | 2.4 (2.4) |
| SES-CD score in ileum at one year, mean (SD) | 3.9 (3.3) | 4.3 (4.0) | 3.5 (2.5) |
| Ileum GHAS score at one year, mean (SD) | 2.7 (3.3) | 2.8 (3.2) | 2.6 (3.4) |
| Endoscopic remission of ileum at week 12, n (%) | 9 (12.7) | 2 (6.5) | 7 (17.5) |
| Endoscopic remission of ileum at one year, n (%) | 12 (16.9) | 7 (22.6) | 5 (12.5) |
| Histologic remission of ileum at week 12, n (%)a | 18 (25.4) | 7 (22.6) | 11 (27.4) |
| Histologic remission of ileum at one year, n (%)a | 26 (36.6) | 11 (35.5) | 15 (37.5) |
aDefined as IGHAS score of 0.
Endoscopic and histologic outcomes attained by study population at week 12 and one year.
| . | All participants (n = 71) . | Adalimumab induction only/placebo (n = 31) . | Adalimumab (n = 40) . |
|---|---|---|---|
| Ileum GHAS score at week 12, mean (SD) | 3.2 (2.8) | 3.8 (3.0) | 2.7 (2.6) |
| SES-CD score in ileum at week 12, mean (SD) | 3.7 (3.0) | 5.1 (3.0) | 2.4 (2.4) |
| SES-CD score in ileum at one year, mean (SD) | 3.9 (3.3) | 4.3 (4.0) | 3.5 (2.5) |
| Ileum GHAS score at one year, mean (SD) | 2.7 (3.3) | 2.8 (3.2) | 2.6 (3.4) |
| Endoscopic remission of ileum at week 12, n (%) | 9 (12.7) | 2 (6.5) | 7 (17.5) |
| Endoscopic remission of ileum at one year, n (%) | 12 (16.9) | 7 (22.6) | 5 (12.5) |
| Histologic remission of ileum at week 12, n (%)a | 18 (25.4) | 7 (22.6) | 11 (27.4) |
| Histologic remission of ileum at one year, n (%)a | 26 (36.6) | 11 (35.5) | 15 (37.5) |
| . | All participants (n = 71) . | Adalimumab induction only/placebo (n = 31) . | Adalimumab (n = 40) . |
|---|---|---|---|
| Ileum GHAS score at week 12, mean (SD) | 3.2 (2.8) | 3.8 (3.0) | 2.7 (2.6) |
| SES-CD score in ileum at week 12, mean (SD) | 3.7 (3.0) | 5.1 (3.0) | 2.4 (2.4) |
| SES-CD score in ileum at one year, mean (SD) | 3.9 (3.3) | 4.3 (4.0) | 3.5 (2.5) |
| Ileum GHAS score at one year, mean (SD) | 2.7 (3.3) | 2.8 (3.2) | 2.6 (3.4) |
| Endoscopic remission of ileum at week 12, n (%) | 9 (12.7) | 2 (6.5) | 7 (17.5) |
| Endoscopic remission of ileum at one year, n (%) | 12 (16.9) | 7 (22.6) | 5 (12.5) |
| Histologic remission of ileum at week 12, n (%)a | 18 (25.4) | 7 (22.6) | 11 (27.4) |
| Histologic remission of ileum at one year, n (%)a | 26 (36.6) | 11 (35.5) | 15 (37.5) |
aDefined as IGHAS score of 0.
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